Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
geh-1Lipase; Identified by similarity to GP:2981225; match to protein family HMM PF04650; match to protein family HMM TIGR01168; Belongs to the AB hydrolase superfamily. Lipase family. (688 aa)    
Predicted Functional Partners:
ypfP
ypfP protein; Processive glucosyltransferase involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. Is able to successively transfer two glucosyl residues to diacylglycerol (DAG), thereby catalyzing the formation of beta-monoglucosyl-DAG (3-O- (beta-D-glucopyranosyl)-1,2-diacyl-sn-glycerol) and beta-diglucosyl-DAG (3-O-(beta-D-glucopyranosyl-beta-(1->6)-D-glucopyranosyl)-1,2-diacyl- sn-glycerol). Beta-diglucosyl-DAG is the predominant glycolipid found in Bacillales and is also used as a membrane anchor for lipoteichoic acid (LTA).
  
  
 0.920
geh-2
Lipase; Identified by similarity to GP:3789932; match to protein family HMM PF04650; match to protein family HMM TIGR01168.
  
  
0.918
SERP0018
Lipase, putative; Identified by match to protein family HMM PF04650; match to protein family HMM TIGR01168.
  
  
 
0.909
SERP2336
Lipase, putative; Identified by similarity to SP:Q02510; match to protein family HMM PF04650; match to protein family HMM TIGR01168.
  
  
 
0.905
dagK
Conserved hypothetical protein TIGR00147; Catalyzes the phosphorylation of diacylglycerol (DAG) into phosphatidic acid. Is a key enzyme involved in the production of lipoteichoic acid by reintroducing DAG formed from the breakdown of membrane phospholipids into the phosphatidylglycerol biosynthetic pathway (By similarity); Belongs to the diacylglycerol/lipid kinase family.
     
 0.901
sdrH
sdrH protein; Identified by similarity to GP:8101009.
  
   
 0.839
vraA
Long chain fatty acid CoA ligase, putative; Identified by match to protein family HMM PF00501; Belongs to the ATP-dependent AMP-binding enzyme family.
    
  0.800
SERP2264
Cell wall surface anchor family protein.
  
     0.760
SERP2063
Esterase, putative; Identified by similarity to SP:P22862.
  
  
 0.734
SERP1779
Conserved hypothetical protein; Identified by similarity to OMNI:SA2169; match to protein family HMM PF04183.
  
     0.722
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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