Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SERP2471Type I restriction-modification system, S subunit, EcoA family. (381 aa)    
Predicted Functional Partners:
hsdM
Type I restriction-modification system, M subunit; Identified by match to protein family HMM PF02384; match to protein family HMM PF02506; match to protein family HMM TIGR00497.
 
 
 0.995
hsdR
Type I restriction-modification system, R subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification; Belongs to the HsdR family.
 
  
 0.988
SERP2473
Hypothetical protein; Identified by Glimmer2; putative.
 
    0.921
SERP2464
Conserved domain protein.
  
 
 0.914
atpF
ATP synthase F0, B subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
   
 
 0.444
SERP2475
Conserved hypothetical protein; Identified by similarity to GP:4894349.
       0.441
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 
 0.418
Your Current Organism:
Staphylococcus epidermidis
NCBI taxonomy Id: 176279
Other names: S. epidermidis RP62A, Staphylococcus epidermidis ATCC 35984, Staphylococcus epidermidis RP62A, Staphylococcus epidermidis str. RP62A, Staphylococcus epidermidis strain RP62A
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