node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SERP2535 | yycF | SERP2535 | SERP2534 | Hypothetical protein; Identified by Glimmer2; putative. | DNA-binding response regulator YycF; Member of the two-component regulatory system WalK/WalR. | 0.636 |
SERP2535 | yycG | SERP2535 | SERP2533 | Hypothetical protein; Identified by Glimmer2; putative. | Sensory box histidine kinase YycG; Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR. | 0.623 |
SERP2535 | yycH | SERP2535 | SERP2532 | Hypothetical protein; Identified by Glimmer2; putative. | yycH protein; Identified by similarity to GP:6689208. | 0.623 |
SERP2535 | yycI | SERP2535 | SERP2531 | Hypothetical protein; Identified by Glimmer2; putative. | yycI protein; Identified by similarity to OMNI:SA0022. | 0.623 |
arlR | yycG | SERP0989 | SERP2533 | DNA-binding response regulator ArlR; Member of the two-component regulatory system ArlS/ArlR. | Sensory box histidine kinase YycG; Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR. | 0.793 |
hssR | yycG | SERP1953 | SERP2533 | DNA-binding response regulator; Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence. Phosphorylated HssR binds to a direct repeat sequence within hrtAB promoter and activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity). | Sensory box histidine kinase YycG; Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR. | 0.607 |
phoP | yycG | SERP1256 | SERP2533 | Alkaline phosphatase synthesis transcriptional regulatory protein PhoP; Identified by similarity to EGAD:18490; match to protein family HMM PF00072; match to protein family HMM PF00486. | Sensory box histidine kinase YycG; Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR. | 0.843 |
saeR | yycG | SERP0365 | SERP2533 | DNA-binding response regulator SaeR; Member of the two-component regulatory system SaeR/SaeS. Probably functions as a transcriptional regulator via a specific DNA- binding domain, recognizing motifs near the promoter sequences of target genes (By similarity). | Sensory box histidine kinase YycG; Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR. | 0.733 |
srrA | yycG | SERP1055 | SERP2533 | DNA-binding response regulator SrrA; Identified by similarity to EGAD:14175; similarity to OMNI:SA1535; match to protein family HMM PF00072; match to protein family HMM PF00486. | Sensory box histidine kinase YycG; Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR. | 0.806 |
yycF | SERP2535 | SERP2534 | SERP2535 | DNA-binding response regulator YycF; Member of the two-component regulatory system WalK/WalR. | Hypothetical protein; Identified by Glimmer2; putative. | 0.636 |
yycF | yycG | SERP2534 | SERP2533 | DNA-binding response regulator YycF; Member of the two-component regulatory system WalK/WalR. | Sensory box histidine kinase YycG; Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR. | 0.999 |
yycF | yycH | SERP2534 | SERP2532 | DNA-binding response regulator YycF; Member of the two-component regulatory system WalK/WalR. | yycH protein; Identified by similarity to GP:6689208. | 0.953 |
yycF | yycI | SERP2534 | SERP2531 | DNA-binding response regulator YycF; Member of the two-component regulatory system WalK/WalR. | yycI protein; Identified by similarity to OMNI:SA0022. | 0.954 |
yycF | yycJ | SERP2534 | SERP2530 | DNA-binding response regulator YycF; Member of the two-component regulatory system WalK/WalR. | Identified by match to protein family HMM PF00753. | 0.761 |
yycG | SERP2535 | SERP2533 | SERP2535 | Sensory box histidine kinase YycG; Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR. | Hypothetical protein; Identified by Glimmer2; putative. | 0.623 |
yycG | arlR | SERP2533 | SERP0989 | Sensory box histidine kinase YycG; Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR. | DNA-binding response regulator ArlR; Member of the two-component regulatory system ArlS/ArlR. | 0.793 |
yycG | hssR | SERP2533 | SERP1953 | Sensory box histidine kinase YycG; Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR. | DNA-binding response regulator; Member of the two-component regulatory system HssS/HssR involved in intracellular heme homeostasis and tempering of staphylococcal virulence. Phosphorylated HssR binds to a direct repeat sequence within hrtAB promoter and activates the expression of hrtAB, an efflux pump, in response to extracellular heme, hemin, hemoglobin or blood (By similarity). | 0.607 |
yycG | phoP | SERP2533 | SERP1256 | Sensory box histidine kinase YycG; Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR. | Alkaline phosphatase synthesis transcriptional regulatory protein PhoP; Identified by similarity to EGAD:18490; match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.843 |
yycG | saeR | SERP2533 | SERP0365 | Sensory box histidine kinase YycG; Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR. | DNA-binding response regulator SaeR; Member of the two-component regulatory system SaeR/SaeS. Probably functions as a transcriptional regulator via a specific DNA- binding domain, recognizing motifs near the promoter sequences of target genes (By similarity). | 0.733 |
yycG | srrA | SERP2533 | SERP1055 | Sensory box histidine kinase YycG; Member of the two-component regulatory system WalK/WalR that regulates genes involved in autolysis, biofilm formation and cell wall metabolism. WalK functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to WalR. | DNA-binding response regulator SrrA; Identified by similarity to EGAD:14175; similarity to OMNI:SA1535; match to protein family HMM PF00072; match to protein family HMM PF00486. | 0.806 |