Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ptsHPhosphocarrier protein HPr. (91 aa)    
Predicted Functional Partners:
Atu0031
PTS system, IIA component.
 
 0.997
ptsI
Phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family.
  
 
 
 0.929
Atu0032
Conserved hypothetical protein.
 
 
 
 0.877
ptsN
Nitrogen regulatory IIA protein.
 
  
 0.836
chvG
Two component sensor kinase; Member of a two-component regulatory system ChvG/ChvI. Activates ChvI by phosphorylation (Potential).
 
   
 0.778
ahcY
S-adenosylhomocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
       0.737
Atu0026
Conserved hypothetical protein.
     
 0.700
Atu0024
Conserved hypothetical protein.
       0.677
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
    0.573
rpsL
30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy.
  
    0.555
Your Current Organism:
Agrobacterium fabrum
NCBI taxonomy Id: 176299
Other names: A. fabrum str. C58, Agrobacterium fabrum str. C58, Agrobacterium tumefaciens (strain C58 / ATCC 33970), Agrobacterium tumefaciens (strain C58), Agrobacterium tumefaciens str. C58, Agrobacterium tumefaciens str. C58 (Cereon), Agrobacterium tumefaciens str. C58 (Dupont), Agrobacterium tumefaciens str. C58 (U. Washington), Rhizobium radiobacter str. C58 (Cereon), Rhizobium radiobacter str. C58 (Dupont), Rhizobium radiobacter str. C58 (U. Washington)
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