STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mmsAMethylmalonate-semialdehyde dehydrogenase. (518 aa)    
Predicted Functional Partners:
mmsB-2
3-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family.
 
 
 0.935
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 0.931
fadB-2
enoyl-CoA hydratase.
  
 0.922
bioA
Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
  
 0.922
Atu3950
Aldehyde dehydrogenase.
  
  
 
0.922
Atu3401
Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.921
Atu4849
NADP-dependent aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.914
bkdB
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex E2.
   
 0.910
Atu3586
propionyl-CoA carboxylase.
   
 0.910
Atu0502
acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.
   
 0.909
Your Current Organism:
Agrobacterium fabrum
NCBI taxonomy Id: 176299
Other names: A. fabrum str. C58, Agrobacterium fabrum str. C58, Agrobacterium tumefaciens (strain C58 / ATCC 33970), Agrobacterium tumefaciens (strain C58), Agrobacterium tumefaciens str. C58, Agrobacterium tumefaciens str. C58 (Cereon), Agrobacterium tumefaciens str. C58 (Dupont), Agrobacterium tumefaciens str. C58 (U. Washington), Rhizobium radiobacter str. C58 (Cereon), Rhizobium radiobacter str. C58 (Dupont), Rhizobium radiobacter str. C58 (U. Washington)
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