| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Atu0527 | aspB | Atu0527 | Atu0529 | Two component sensor kinase/response regulator hybrid. | Aspartate transaminase. | 0.460 |
| Atu0527 | dctA | Atu0527 | Atu3298 | Two component sensor kinase/response regulator hybrid. | C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.487 |
| Atu0527 | mscL | Atu0527 | Atu0528 | Two component sensor kinase/response regulator hybrid. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.700 |
| Atu0527 | ppa | Atu0527 | Atu2661 | Two component sensor kinase/response regulator hybrid. | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.452 |
| Atu2682 | mscL | Atu2682 | Atu0528 | Conserved hypothetical protein; Belongs to the BI1 family. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.510 |
| aspB | Atu0527 | Atu0529 | Atu0527 | Aspartate transaminase. | Two component sensor kinase/response regulator hybrid. | 0.460 |
| aspB | mscL | Atu0529 | Atu0528 | Aspartate transaminase. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.709 |
| dctA | Atu0527 | Atu3298 | Atu0527 | C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Two component sensor kinase/response regulator hybrid. | 0.487 |
| dctA | mscL | Atu3298 | Atu0528 | C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.539 |
| dctA | ppa | Atu3298 | Atu2661 | C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.444 |
| folC | mscL | Atu0021 | Atu0528 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.505 |
| folC | ppa | Atu0021 | Atu2661 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. | 0.491 |
| folC | recN | Atu0021 | Atu2083 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.593 |
| metK | mscL | Atu0362 | Atu0528 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | 0.746 |
| metK | ribH | Atu0362 | Atu1171 | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. | Riboflavin synthase beta chain; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.955 |
| mscL | Atu0527 | Atu0528 | Atu0527 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Two component sensor kinase/response regulator hybrid. | 0.700 |
| mscL | Atu2682 | Atu0528 | Atu2682 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Conserved hypothetical protein; Belongs to the BI1 family. | 0.510 |
| mscL | aspB | Atu0528 | Atu0529 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Aspartate transaminase. | 0.709 |
| mscL | dctA | Atu0528 | Atu3298 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | C4-dicarboxylate transport protein; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. | 0.539 |
| mscL | folC | Atu0528 | Atu0021 | Large conductance mechanosensitive channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.505 |