| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Atu1043 | Atu1285 | Atu1043 | Atu1285 | Conserved hypothetical protein. | Metal dependent hydrolase. | 0.508 |
| Atu1043 | ybeY | Atu1043 | Atu0358 | Conserved hypothetical protein. | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.425 |
| Atu1285 | Atu1043 | Atu1285 | Atu1043 | Metal dependent hydrolase. | Conserved hypothetical protein. | 0.508 |
| Atu1285 | Atu1286 | Atu1285 | Atu1286 | Metal dependent hydrolase. | Conserved hypothetical protein. | 0.533 |
| Atu1285 | birA | Atu1285 | Atu1284 | Metal dependent hydrolase. | birA bifunctional protein. | 0.752 |
| Atu1285 | ispA | Atu1285 | Atu2721 | Metal dependent hydrolase. | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.653 |
| Atu1285 | ispB | Atu1285 | Atu0634 | Metal dependent hydrolase. | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.653 |
| Atu1285 | ksgA | Atu1285 | Atu1103 | Metal dependent hydrolase. | rRNA-adenine N6,N6-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.596 |
| Atu1285 | nuoN | Atu1285 | Atu1283 | Metal dependent hydrolase. | NADH ubiquinone oxidoreductase chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. | 0.532 |
| Atu1285 | rpmI | Atu1285 | Atu0255 | Metal dependent hydrolase. | 50S ribosomal protein L35; Belongs to the bacterial ribosomal protein bL35 family. | 0.530 |
| Atu1285 | topA | Atu1285 | Atu1304 | Metal dependent hydrolase. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.532 |
| Atu1285 | ybeY | Atu1285 | Atu0358 | Metal dependent hydrolase. | Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.521 |
| Atu1286 | Atu1285 | Atu1286 | Atu1285 | Conserved hypothetical protein. | Metal dependent hydrolase. | 0.533 |
| birA | Atu1285 | Atu1284 | Atu1285 | birA bifunctional protein. | Metal dependent hydrolase. | 0.752 |
| birA | nuoN | Atu1284 | Atu1283 | birA bifunctional protein. | NADH ubiquinone oxidoreductase chain N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. | 0.843 |
| ispA | Atu1285 | Atu2721 | Atu1285 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Metal dependent hydrolase. | 0.653 |
| ispA | ispB | Atu2721 | Atu0634 | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.925 |
| ispB | Atu1285 | Atu0634 | Atu1285 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Metal dependent hydrolase. | 0.653 |
| ispB | ispA | Atu0634 | Atu2721 | Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Geranyltranstransferase; Belongs to the FPP/GGPP synthase family. | 0.925 |
| ksgA | Atu1285 | Atu1103 | Atu1285 | rRNA-adenine N6,N6-dimethyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Metal dependent hydrolase. | 0.596 |