node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atu1632 | gcvH | Atu1632 | Atu1463 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Glycine cleavage system component H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.882 |
Atu1632 | gcvP | Atu1632 | Atu1462 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.991 |
Atu1632 | glyA | Atu1632 | Atu1165 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.563 |
Atu1632 | glyA-2 | Atu1632 | Atu4314 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.563 |
Atu1632 | soxA | Atu1632 | Atu4069 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase alpha subunit. | 0.981 |
Atu1632 | soxA-2 | Atu1632 | Atu4222 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase alpha subunit. | 0.823 |
Atu1632 | soxA-3 | Atu1632 | Atu4312 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase alpha subunit. | 0.980 |
gcvH | Atu1632 | Atu1463 | Atu1632 | Glycine cleavage system component H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.882 |
gcvH | gcvP | Atu1463 | Atu1462 | Glycine cleavage system component H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
gcvH | gcvT-2 | Atu1463 | Atu1420 | Glycine cleavage system component H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system T protein, aminomethyltransferase; Belongs to the GcvT family. | 0.877 |
gcvH | gcvT-3 | Atu1463 | Atu1464 | Glycine cleavage system component H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Glycine cleavage system T protein, aminomethyltransferase. | 0.999 |
gcvH | glyA | Atu1463 | Atu1165 | Glycine cleavage system component H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.956 |
gcvH | glyA-2 | Atu1463 | Atu4314 | Glycine cleavage system component H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.956 |
gcvH | purD | Atu1463 | Atu0647 | Glycine cleavage system component H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Phosphoribosylamine--glycine ligase. | 0.417 |
gcvH | soxA | Atu1463 | Atu4069 | Glycine cleavage system component H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Sarcosine oxidase alpha subunit. | 0.884 |
gcvH | soxA-2 | Atu1463 | Atu4222 | Glycine cleavage system component H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Sarcosine oxidase alpha subunit. | 0.897 |
gcvH | soxA-3 | Atu1463 | Atu4312 | Glycine cleavage system component H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Sarcosine oxidase alpha subunit. | 0.884 |
gcvP | Atu1632 | Atu1462 | Atu1632 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.991 |
gcvP | gcvH | Atu1462 | Atu1463 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine cleavage system component H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
gcvP | gcvT-2 | Atu1462 | Atu1420 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine cleavage system T protein, aminomethyltransferase; Belongs to the GcvT family. | 0.990 |