Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gguCConserved hypothetical protein. (348 aa)    
Predicted Functional Partners:
gguA
ABC transporter, nucleotide binding/ATPase protein (sugar).
 
   
 0.875
gguB
ABC transporter, membrane spanning protein (sugar); Belongs to the binding-protein-dependent transport system permease family.
 
   
 0.832
chvE
Sugar binding protein; Required for effective transcriptional induction of the vir genes by monosaccharides in response to plant signals and for normal growth and chemotaxis towards certain sugars. Functions as a periplasmic multiple sugar-binding receptor protein. It does not interact with a transport system.
 
   
 0.770
Atu1113
Dehydrogenase.
 
    0.679
Atu2741
Conserved hypothetical protein.
 
     0.658
gbpR
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
 
     0.565
pdxA
Pyridoxal phosphate biosynthesis protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
  
  
 0.522
xylF
ABC transporter, substrate binding protein (xylose).
     
 0.506
xylG
ABC transporter, nucleotide binding/ATPase protein (xylose).
     
 0.463
Atu3817
Dehydratase.
     
 0.456
Your Current Organism:
Agrobacterium fabrum
NCBI taxonomy Id: 176299
Other names: A. fabrum str. C58, Agrobacterium fabrum str. C58, Agrobacterium tumefaciens (strain C58 / ATCC 33970), Agrobacterium tumefaciens (strain C58), Agrobacterium tumefaciens str. C58, Agrobacterium tumefaciens str. C58 (Cereon), Agrobacterium tumefaciens str. C58 (Dupont), Agrobacterium tumefaciens str. C58 (U. Washington), Rhizobium radiobacter str. C58 (Cereon), Rhizobium radiobacter str. C58 (Dupont), Rhizobium radiobacter str. C58 (U. Washington)
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