Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ordL-3Oxidoreductase. (427 aa)    
Predicted Functional Partners:
Atu4676
Putative malate dehydrogenase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L- proline (t3LHyp) to L-proline, which would allow A.tumefaciens to grow on t3LHyp as a sole carbon source; Belongs to the LDH2/MDH2 oxidoreductase family.
     
  0.900
soxA
Sarcosine oxidase alpha subunit.
  
 
 0.707
soxA-2
Sarcosine oxidase alpha subunit.
  
 
 0.707
soxA-3
Sarcosine oxidase alpha subunit.
  
 
 0.707
Atu2559
Transcriptional regulator, LysR family; Belongs to the LysR transcriptional regulatory family.
 
     0.665
modA
ABC transporter, substrate binding protein (molybdate).
  
    0.629
glnA-2
Glutamine synthetase.
 
  
 0.593
Atu1002
Aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
     0.559
Atu2558
Transcriptional regulator, Lrp family.
       0.487
Atu3369
Conserved hypothetical protein.
 
  
 0.482
Your Current Organism:
Agrobacterium fabrum
NCBI taxonomy Id: 176299
Other names: A. fabrum str. C58, Agrobacterium fabrum str. C58, Agrobacterium tumefaciens (strain C58 / ATCC 33970), Agrobacterium tumefaciens (strain C58), Agrobacterium tumefaciens str. C58, Agrobacterium tumefaciens str. C58 (Cereon), Agrobacterium tumefaciens str. C58 (Dupont), Agrobacterium tumefaciens str. C58 (U. Washington), Rhizobium radiobacter str. C58 (Cereon), Rhizobium radiobacter str. C58 (Dupont), Rhizobium radiobacter str. C58 (U. Washington)
Server load: low (12%) [HD]