| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Atu2656 | guaA-3 | Atu2656 | Atu2658 | Conserved hypothetical protein. | GMP synthase - glutamine amidotransferase protein. | 0.899 |
| Atu3770 | gmk-2 | Atu3770 | Atu1101 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.900 |
| Atu3770 | gpt | Atu3770 | Atu1731 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.905 |
| Atu3770 | guaA-2 | Atu3770 | Atu0281 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.904 |
| Atu3770 | guaA-3 | Atu3770 | Atu2658 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | GMP synthase - glutamine amidotransferase protein. | 0.903 |
| Atu3770 | guaB | Atu3770 | Atu0624 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.913 |
| Atu3770 | ham1 | Atu3770 | Atu0326 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Putative deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.900 |
| Atu3770 | hpt | Atu3770 | Atu3604 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.900 |
| Atu3770 | mazG | Atu3770 | Atu1452 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Conserved hypothetical protein. | 0.901 |
| Atu3770 | surE | Atu3770 | Atu1702 | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | Stationary-phase survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.912 |
| gmk-2 | Atu3770 | Atu1101 | Atu3770 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.900 |
| gmk-2 | gpt | Atu1101 | Atu1731 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.948 |
| gmk-2 | guaA-2 | Atu1101 | Atu0281 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.974 |
| gmk-2 | guaA-3 | Atu1101 | Atu2658 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | GMP synthase - glutamine amidotransferase protein. | 0.915 |
| gmk-2 | guaB | Atu1101 | Atu0624 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Inosine-5`-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.597 |
| gmk-2 | hpt | Atu1101 | Atu3604 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.943 |
| gmk-2 | mazG | Atu1101 | Atu1452 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Conserved hypothetical protein. | 0.901 |
| gmk-2 | surE | Atu1101 | Atu1702 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Stationary-phase survival protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.912 |
| gpt | Atu3770 | Atu1731 | Atu3770 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 5'-nucleotidase; Belongs to the 5'-nucleotidase family. | 0.905 |
| gpt | gmk-2 | Atu1731 | Atu1101 | Xanthine-guanine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.948 |