node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atu3593 | cbiP | Atu3593 | Atu2808 | Conserved hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.924 |
Atu3593 | cobB | Atu3593 | Atu2793 | Conserved hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.922 |
Atu3593 | cobC | Atu3593 | Atu2810 | Conserved hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin biosynthetic protein. | 0.916 |
Atu3593 | cobD | Atu3593 | Atu2809 | Conserved hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.922 |
Atu3593 | cobL | Atu3593 | Atu2798 | Conserved hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | Precorrin-6y methyltransferase. | 0.577 |
Atu3593 | cobO | Atu3593 | Atu2807 | Conserved hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.940 |
Atu3593 | cobP | Atu3593 | Atu1542 | Conserved hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | Bifunctional adenosylcobalamin biosynthesis protein cobP; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.928 |
Atu3593 | cobS | Atu3593 | Atu1891 | Conserved hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin biosynthesis protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.930 |
cbiC | cbiP | Atu2802 | Atu2808 | precorrin-8X methylmutase. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.979 |
cbiC | cobB | Atu2802 | Atu2793 | precorrin-8X methylmutase. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.994 |
cbiC | cobC | Atu2802 | Atu2810 | precorrin-8X methylmutase. | Cobalamin biosynthetic protein. | 0.504 |
cbiC | cobD | Atu2802 | Atu2809 | precorrin-8X methylmutase. | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.912 |
cbiC | cobL | Atu2802 | Atu2798 | precorrin-8X methylmutase. | Precorrin-6y methyltransferase. | 0.999 |
cbiC | cobO | Atu2802 | Atu2807 | precorrin-8X methylmutase. | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.610 |
cbiC | cobP | Atu2802 | Atu1542 | precorrin-8X methylmutase. | Bifunctional adenosylcobalamin biosynthesis protein cobP; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.727 |
cbiC | cobS | Atu2802 | Atu1891 | precorrin-8X methylmutase. | Cobalamin biosynthesis protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.794 |
cbiC | cobT | Atu2802 | Atu1890 | precorrin-8X methylmutase. | Cobyrinic acid synthase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.698 |
cbiP | Atu3593 | Atu2808 | Atu3593 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Conserved hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.924 |
cbiP | cbiC | Atu2808 | Atu2802 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | precorrin-8X methylmutase. | 0.979 |
cbiP | cobB | Atu2808 | Atu2793 | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.961 |