node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atu3135 | Atu3137 | Atu3135 | Atu3137 | ABC transporter, membrane spanning protein. | C4-dicarboxylate-binding protein. | 0.952 |
Atu3135 | Atu3138 | Atu3135 | Atu3138 | ABC transporter, membrane spanning protein. | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | 0.644 |
Atu3135 | kduI | Atu3135 | Atu3142 | ABC transporter, membrane spanning protein. | 4-deoxy-L-threo-5-hexosulose-uronate; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. | 0.461 |
Atu3135 | udh | Atu3135 | Atu3143 | ABC transporter, membrane spanning protein. | Conserved hypothetical protein; Catalyzes the oxidation of D-galacturonate and D-glucuronate to galactarate and D-glucarate, respectively. In fact, in water solution the substrate D-galacturonate is predominantly in pyranosic form whose beta anomer is converted by the enzyme to D-galactaro-1,5- lactone; in solution, this reaction product rearranges to the more stable D-galactaro-1,4-lactone. Makes part of the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. Cannot use NADP(+) instead of NAD(+) as cosubstra [...] | 0.449 |
Atu3137 | Atu3135 | Atu3137 | Atu3135 | C4-dicarboxylate-binding protein. | ABC transporter, membrane spanning protein. | 0.952 |
Atu3137 | Atu3138 | Atu3137 | Atu3138 | C4-dicarboxylate-binding protein. | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | 0.655 |
Atu3137 | Atu3140 | Atu3137 | Atu3140 | C4-dicarboxylate-binding protein. | 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. | 0.459 |
Atu3137 | gci | Atu3137 | Atu3139 | C4-dicarboxylate-binding protein. | Conserved hypothetical protein; Catalyzes the ring opening of D-galactaro-1,4-lactone to yield 5-keto-4-deoxy-D-glucarate (KDG) via a beta-elimination reaction. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D-galacturonate as a sole carbon source. To a lesser extent, can also use D-glucaro-1,4-lactone as substrate to produce KDG, but cannot use D-galactaro-1,5-lactone, D- glucaro-6,3-lactone and linear D-glucarate. | 0.495 |
Atu3137 | kduD | Atu3137 | Atu3141 | C4-dicarboxylate-binding protein. | 2-deoxy-D-gluconate 3-dehydrogenase. | 0.434 |
Atu3137 | kduI | Atu3137 | Atu3142 | C4-dicarboxylate-binding protein. | 4-deoxy-L-threo-5-hexosulose-uronate; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. | 0.580 |
Atu3137 | udh | Atu3137 | Atu3143 | C4-dicarboxylate-binding protein. | Conserved hypothetical protein; Catalyzes the oxidation of D-galacturonate and D-glucuronate to galactarate and D-glucarate, respectively. In fact, in water solution the substrate D-galacturonate is predominantly in pyranosic form whose beta anomer is converted by the enzyme to D-galactaro-1,5- lactone; in solution, this reaction product rearranges to the more stable D-galactaro-1,4-lactone. Makes part of the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. Cannot use NADP(+) instead of NAD(+) as cosubstra [...] | 0.566 |
Atu3138 | Atu3135 | Atu3138 | Atu3135 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | ABC transporter, membrane spanning protein. | 0.644 |
Atu3138 | Atu3137 | Atu3138 | Atu3137 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | C4-dicarboxylate-binding protein. | 0.655 |
Atu3138 | Atu3140 | Atu3138 | Atu3140 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. | 0.949 |
Atu3138 | Atu3144 | Atu3138 | Atu3144 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | Transcriptional regulator, GntR family. | 0.575 |
Atu3138 | Atu3972 | Atu3138 | Atu3972 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | Conserved hypothetical protein. | 0.985 |
Atu3138 | gci | Atu3138 | Atu3139 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | Conserved hypothetical protein; Catalyzes the ring opening of D-galactaro-1,4-lactone to yield 5-keto-4-deoxy-D-glucarate (KDG) via a beta-elimination reaction. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D-galacturonate as a sole carbon source. To a lesser extent, can also use D-glucaro-1,4-lactone as substrate to produce KDG, but cannot use D-galactaro-1,5-lactone, D- glucaro-6,3-lactone and linear D-glucarate. | 0.995 |
Atu3138 | kduD | Atu3138 | Atu3141 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | 2-deoxy-D-gluconate 3-dehydrogenase. | 0.706 |
Atu3138 | kduI | Atu3138 | Atu3142 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | 4-deoxy-L-threo-5-hexosulose-uronate; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family. | 0.697 |
Atu3138 | macA | Atu3138 | Atu2528 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | Maleylacetate reductase. | 0.565 |