node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atu3138 | Atu3140 | Atu3138 | Atu3140 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. | 0.949 |
Atu3138 | Atu3144 | Atu3138 | Atu3144 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | Transcriptional regulator, GntR family. | 0.575 |
Atu3138 | Atu3972 | Atu3138 | Atu3972 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | Conserved hypothetical protein. | 0.985 |
Atu3138 | gci | Atu3138 | Atu3139 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | Conserved hypothetical protein; Catalyzes the ring opening of D-galactaro-1,4-lactone to yield 5-keto-4-deoxy-D-glucarate (KDG) via a beta-elimination reaction. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D-galacturonate as a sole carbon source. To a lesser extent, can also use D-glucaro-1,4-lactone as substrate to produce KDG, but cannot use D-galactaro-1,5-lactone, D- glucaro-6,3-lactone and linear D-glucarate. | 0.995 |
Atu3138 | udh | Atu3138 | Atu3143 | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | Conserved hypothetical protein; Catalyzes the oxidation of D-galacturonate and D-glucuronate to galactarate and D-glucarate, respectively. In fact, in water solution the substrate D-galacturonate is predominantly in pyranosic form whose beta anomer is converted by the enzyme to D-galactaro-1,5- lactone; in solution, this reaction product rearranges to the more stable D-galactaro-1,4-lactone. Makes part of the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. Cannot use NADP(+) instead of NAD(+) as cosubstra [...] | 0.989 |
Atu3140 | Atu3138 | Atu3140 | Atu3138 | 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | 0.949 |
Atu3140 | Atu3144 | Atu3140 | Atu3144 | 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. | Transcriptional regulator, GntR family. | 0.627 |
Atu3140 | Atu3972 | Atu3140 | Atu3972 | 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. | Conserved hypothetical protein. | 0.711 |
Atu3140 | gci | Atu3140 | Atu3139 | 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. | Conserved hypothetical protein; Catalyzes the ring opening of D-galactaro-1,4-lactone to yield 5-keto-4-deoxy-D-glucarate (KDG) via a beta-elimination reaction. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D-galacturonate as a sole carbon source. To a lesser extent, can also use D-glucaro-1,4-lactone as substrate to produce KDG, but cannot use D-galactaro-1,5-lactone, D- glucaro-6,3-lactone and linear D-glucarate. | 0.991 |
Atu3140 | rpsC | Atu3140 | Atu1940 | 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.406 |
Atu3140 | udh | Atu3140 | Atu3143 | 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. | Conserved hypothetical protein; Catalyzes the oxidation of D-galacturonate and D-glucuronate to galactarate and D-glucarate, respectively. In fact, in water solution the substrate D-galacturonate is predominantly in pyranosic form whose beta anomer is converted by the enzyme to D-galactaro-1,5- lactone; in solution, this reaction product rearranges to the more stable D-galactaro-1,4-lactone. Makes part of the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. Cannot use NADP(+) instead of NAD(+) as cosubstra [...] | 0.817 |
Atu3144 | Atu3138 | Atu3144 | Atu3138 | Transcriptional regulator, GntR family. | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | 0.575 |
Atu3144 | Atu3140 | Atu3144 | Atu3140 | Transcriptional regulator, GntR family. | 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. | 0.627 |
Atu3144 | gci | Atu3144 | Atu3139 | Transcriptional regulator, GntR family. | Conserved hypothetical protein; Catalyzes the ring opening of D-galactaro-1,4-lactone to yield 5-keto-4-deoxy-D-glucarate (KDG) via a beta-elimination reaction. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D-galacturonate as a sole carbon source. To a lesser extent, can also use D-glucaro-1,4-lactone as substrate to produce KDG, but cannot use D-galactaro-1,5-lactone, D- glucaro-6,3-lactone and linear D-glucarate. | 0.425 |
Atu3144 | udh | Atu3144 | Atu3143 | Transcriptional regulator, GntR family. | Conserved hypothetical protein; Catalyzes the oxidation of D-galacturonate and D-glucuronate to galactarate and D-glucarate, respectively. In fact, in water solution the substrate D-galacturonate is predominantly in pyranosic form whose beta anomer is converted by the enzyme to D-galactaro-1,5- lactone; in solution, this reaction product rearranges to the more stable D-galactaro-1,4-lactone. Makes part of the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. Cannot use NADP(+) instead of NAD(+) as cosubstra [...] | 0.646 |
Atu3972 | Atu3138 | Atu3972 | Atu3138 | Conserved hypothetical protein. | Conserved hypothetical protein; Catalyzes the isomerization of D-galactaro-1,5-lactone to D- galactaro-1,4-lactone. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D- galacturonate as a sole carbon source. | 0.985 |
Atu3972 | Atu3140 | Atu3972 | Atu3140 | Conserved hypothetical protein. | 5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family. | 0.711 |
Atu3972 | gci | Atu3972 | Atu3139 | Conserved hypothetical protein. | Conserved hypothetical protein; Catalyzes the ring opening of D-galactaro-1,4-lactone to yield 5-keto-4-deoxy-D-glucarate (KDG) via a beta-elimination reaction. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D-galacturonate as a sole carbon source. To a lesser extent, can also use D-glucaro-1,4-lactone as substrate to produce KDG, but cannot use D-galactaro-1,5-lactone, D- glucaro-6,3-lactone and linear D-glucarate. | 0.664 |
Atu3972 | rpsC | Atu3972 | Atu1940 | Conserved hypothetical protein. | 30S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.643 |
Atu3972 | rpsL | Atu3972 | Atu1951 | Conserved hypothetical protein. | 30S ribosomal protein S12; With S4 and S5 plays an important role in translational accuracy. | 0.641 |