STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Atu3259Dehydrogenase. (503 aa)    
Predicted Functional Partners:
Atu3140
5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family.
 
 
 0.949
sucA
Oxoglutarate dehydrogenase E1 component.
   
 
 0.824
icdA
Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family.
   
 0.818
dadA-2
D-amino acid dehydrogenase, small subunit.
  
    0.602
Atu3953
Conserved hypothetical protein; Belongs to the proline racemase family.
 
 
   0.570
Atu0527
Two component sensor kinase/response regulator hybrid.
  
 
 0.562
Atu3364
D-amino acid dehydrogenase.
  
    0.554
Atu4684
Conserved hypothetical protein; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Can also catalyze the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4- hydroxy-D-proline (c4DHyp), albeit with 30-fold lower efficiency. Is likely involved in both degradation pathways that convert t3LHyp to L- proline and t4LHyp to alpha-ketoglutarate, which would allow A.tumefaciens to grow on t3LHyp or t4LHyp as a sole carbon source. Displays no proline racemase activity.
 
 
   0.549
Atu3258
Hypothetical protein.
       0.531
Atu2741
Conserved hypothetical protein.
 
  
 0.524
Your Current Organism:
Agrobacterium fabrum
NCBI taxonomy Id: 176299
Other names: A. fabrum str. C58, Agrobacterium fabrum str. C58, Agrobacterium tumefaciens (strain C58 / ATCC 33970), Agrobacterium tumefaciens (strain C58), Agrobacterium tumefaciens str. C58, Agrobacterium tumefaciens str. C58 (Cereon), Agrobacterium tumefaciens str. C58 (Dupont), Agrobacterium tumefaciens str. C58 (U. Washington), Rhizobium radiobacter str. C58 (Cereon), Rhizobium radiobacter str. C58 (Dupont), Rhizobium radiobacter str. C58 (U. Washington)
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