Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
bkdA22-oxoisovalerate dehydrogenase beta subunit. (337 aa)    
Predicted Functional Partners:
bkdB
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex E2.
 
 0.999
bkdA1
2-oxoisovalerate dehydrogenase alpha subunit.
 0.999
pdhA
Pyruvate dehydrogenase alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.998
lpdA
Dihydrolipoamide dehydrogenase.
 
 0.991
lpdA-2
Dihydrolipoamide dehydrogenase.
 
 0.987
aceF
Dihydrolipoamide acetyltransferase.
 
 0.957
sucB
Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.947
ilvE
Branched-chain-amino-acid aminotransferase.
   
 0.922
mmgC-2
acyl-CoA dehydrogenase.
  
 0.881
gor
Glutathione reductase; Maintains high levels of reduced glutathione.
 
 0.869
Your Current Organism:
Agrobacterium fabrum
NCBI taxonomy Id: 176299
Other names: A. fabrum str. C58, Agrobacterium fabrum str. C58, Agrobacterium tumefaciens (strain C58 / ATCC 33970), Agrobacterium tumefaciens (strain C58), Agrobacterium tumefaciens str. C58, Agrobacterium tumefaciens str. C58 (Cereon), Agrobacterium tumefaciens str. C58 (Dupont), Agrobacterium tumefaciens str. C58 (U. Washington), Rhizobium radiobacter str. C58 (Cereon), Rhizobium radiobacter str. C58 (Dupont), Rhizobium radiobacter str. C58 (U. Washington)
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