Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mccA3-methylcrotonyl-CoA carboxylase alpha subunit. (663 aa)    
Predicted Functional Partners:
mccB
3-methylcrotonoyl-CoA carboxylase beta subunit.
 0.999
acd-7
acyl-CoA dehydrogenase.
 
 0.985
hmgL
hydroxymethylglutaryl-CoA lyase.
  
 0.960
fadB-2
enoyl-CoA hydratase.
  
 0.943
fadB
Enoyl CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family.
  
 0.929
Atu4276
Conserved hypothetical protein.
 
 
 0.925
Atu3481
Enoyl-CoA hydratase/isomerase family protein.
 
 0.921
accD
Acetyl-coenzyme A carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
 
 0.915
acd-4
acyl-CoA dehydrogenase.
  
 0.914
Atu3586
propionyl-CoA carboxylase.
 
 0.914
Your Current Organism:
Agrobacterium fabrum
NCBI taxonomy Id: 176299
Other names: A. fabrum str. C58, Agrobacterium fabrum str. C58, Agrobacterium tumefaciens (strain C58 / ATCC 33970), Agrobacterium tumefaciens (strain C58), Agrobacterium tumefaciens str. C58, Agrobacterium tumefaciens str. C58 (Cereon), Agrobacterium tumefaciens str. C58 (Dupont), Agrobacterium tumefaciens str. C58 (U. Washington), Rhizobium radiobacter str. C58 (Cereon), Rhizobium radiobacter str. C58 (Dupont), Rhizobium radiobacter str. C58 (U. Washington)
Server load: low (18%) [HD]