node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atu3740 | pfp | Atu3740 | Atu2115 | Fructose bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.946 |
Atu3740 | pgi | Atu3740 | Atu0404 | Fructose bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Glucose-6-phosphate isomerase. | 0.940 |
Atu3740 | suhB | Atu3740 | Atu3748 | Fructose bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | Extragenic suppressor protein SuhB; Belongs to the inositol monophosphatase superfamily. | 0.537 |
Atu3875 | pfp | Atu3875 | Atu2115 | Aldolase. | Pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.651 |
Atu3875 | suhB | Atu3875 | Atu3748 | Aldolase. | Extragenic suppressor protein SuhB; Belongs to the inositol monophosphatase superfamily. | 0.512 |
enhC | suhB | Atu3749 | Atu3748 | Enhanced entry protein. | Extragenic suppressor protein SuhB; Belongs to the inositol monophosphatase superfamily. | 0.522 |
idhA | iolG | Atu4012 | Atu4554 | Myo-inositol 2-dehydrogenase. | Myo-inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). | 0.927 |
idhA | suhB | Atu4012 | Atu3748 | Myo-inositol 2-dehydrogenase. | Extragenic suppressor protein SuhB; Belongs to the inositol monophosphatase superfamily. | 0.901 |
iolG | idhA | Atu4554 | Atu4012 | Myo-inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). | Myo-inositol 2-dehydrogenase. | 0.927 |
iolG | suhB | Atu4554 | Atu3748 | Myo-inositol 2-dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). | Extragenic suppressor protein SuhB; Belongs to the inositol monophosphatase superfamily. | 0.900 |
metZ | serC | Atu0432 | Atu3707 | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.629 |
metZ | suhB | Atu0432 | Atu3748 | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | Extragenic suppressor protein SuhB; Belongs to the inositol monophosphatase superfamily. | 0.514 |
metZ | thiC | Atu0432 | Atu2569 | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. | Thiamine biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.526 |
pfp | Atu3740 | Atu2115 | Atu3740 | Pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | Fructose bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.946 |
pfp | Atu3875 | Atu2115 | Atu3875 | Pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | Aldolase. | 0.651 |
pfp | pgi | Atu2115 | Atu0404 | Pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | Glucose-6-phosphate isomerase. | 0.991 |
pfp | suhB | Atu2115 | Atu3748 | Pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | Extragenic suppressor protein SuhB; Belongs to the inositol monophosphatase superfamily. | 0.521 |
pgi | Atu3740 | Atu0404 | Atu3740 | Glucose-6-phosphate isomerase. | Fructose bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. | 0.940 |
pgi | pfp | Atu0404 | Atu2115 | Glucose-6-phosphate isomerase. | Pyrophosphate--fructose-6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. | 0.991 |
pgi | suhB | Atu0404 | Atu3748 | Glucose-6-phosphate isomerase. | Extragenic suppressor protein SuhB; Belongs to the inositol monophosphatase superfamily. | 0.527 |