Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Atu3817Dehydratase. (503 aa)    
Predicted Functional Partners:
uxaB
Altronate oxidoreductase.
 
 0.873
kduI
4-deoxy-L-threo-5-hexosulose-uronate; Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate. Belongs to the KduI family.
 
  
 0.741
kdgK
2-dehydro-3-deoxygluconokinase.
 
  
 0.672
kduD
2-deoxy-D-gluconate 3-dehydrogenase.
 
   
 0.617
gci
Conserved hypothetical protein; Catalyzes the ring opening of D-galactaro-1,4-lactone to yield 5-keto-4-deoxy-D-glucarate (KDG) via a beta-elimination reaction. This is a step in the oxidative degradation pathway of D-galacturonate, which allows A.tumefaciens to utilize D-galacturonate as a sole carbon source. To a lesser extent, can also use D-glucaro-1,4-lactone as substrate to produce KDG, but cannot use D-galactaro-1,5-lactone, D- glucaro-6,3-lactone and linear D-glucarate.
 
  
 0.584
Atu4120
Mandelate racemase; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
  
 0.557
Atu4196
Conserved hypothetical protein; Belongs to the mandelate racemase/muconate lactonizing enzyme family.
 
  
 0.542
rbsA-3
ABC transporter, nucleotide binding/ATPase protein (ribose); Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and/or methyl galactoside import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Carbohydrate importer 2 (CUT2) (TC 3.A.1.2) family.
  
    0.503
Atu3140
5-dehydro-4-deoxyglucarate dehydratase; Belongs to the DapA family.
     
 0.495
rbsC-3
ABC transporter, membrane spanning protein (ribose); Belongs to the binding-protein-dependent transport system permease family.
  
    0.495
Your Current Organism:
Agrobacterium fabrum
NCBI taxonomy Id: 176299
Other names: A. fabrum str. C58, Agrobacterium fabrum str. C58, Agrobacterium tumefaciens (strain C58 / ATCC 33970), Agrobacterium tumefaciens (strain C58), Agrobacterium tumefaciens str. C58, Agrobacterium tumefaciens str. C58 (Cereon), Agrobacterium tumefaciens str. C58 (Dupont), Agrobacterium tumefaciens str. C58 (U. Washington), Rhizobium radiobacter str. C58 (Cereon), Rhizobium radiobacter str. C58 (Dupont), Rhizobium radiobacter str. C58 (U. Washington)
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