| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Atu1632 | gcvP | Atu1632 | Atu1462 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.979 |
| Atu1632 | glyA | Atu1632 | Atu1165 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.950 |
| Atu1632 | soxA | Atu1632 | Atu4069 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase alpha subunit. | 0.979 |
| Atu1632 | soxB | Atu1632 | Atu4066 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase beta subunit. | 0.931 |
| Atu1632 | soxB-3 | Atu1632 | Atu4310 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase beta subunit. | 0.930 |
| Atu1632 | soxD | Atu1632 | Atu4068 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase delta subunit. | 0.987 |
| Atu1632 | soxD-2 | Atu1632 | Atu4223 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase delta subunit. | 0.872 |
| Atu1632 | soxD-3 | Atu1632 | Atu4311 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase delta subunit. | 0.985 |
| Atu1632 | soxG | Atu1632 | Atu4070 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase gamma subunit. | 0.980 |
| Atu1632 | soxG-2 | Atu1632 | Atu4313 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase gamma subunit. | 0.972 |
| gcvP | Atu1632 | Atu1462 | Atu1632 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.979 |
| gcvP | glyA | Atu1462 | Atu1165 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.995 |
| gcvP | soxA | Atu1462 | Atu4069 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase alpha subunit. | 0.998 |
| gcvP | soxB | Atu1462 | Atu4066 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase beta subunit. | 0.905 |
| gcvP | soxB-3 | Atu1462 | Atu4310 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase beta subunit. | 0.905 |
| gcvP | soxD | Atu1462 | Atu4068 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase delta subunit. | 0.903 |
| gcvP | soxD-3 | Atu1462 | Atu4311 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase delta subunit. | 0.903 |
| gcvP | soxG | Atu1462 | Atu4070 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase gamma subunit. | 0.904 |
| gcvP | soxG-2 | Atu1462 | Atu4313 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase gamma subunit. | 0.904 |
| glyA | Atu1632 | Atu1165 | Atu1632 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.950 |