| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Atu4221 | gcvP | Atu4221 | Atu1462 | Conserved hypothetical protein. | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.907 |
| Atu4221 | glyA-2 | Atu4221 | Atu4314 | Conserved hypothetical protein. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.906 |
| Atu4221 | soxA-3 | Atu4221 | Atu4312 | Conserved hypothetical protein. | Sarcosine oxidase alpha subunit. | 0.992 |
| Atu4221 | soxB | Atu4221 | Atu4066 | Conserved hypothetical protein. | Sarcosine oxidase beta subunit. | 0.922 |
| Atu4221 | soxB-3 | Atu4221 | Atu4310 | Conserved hypothetical protein. | Sarcosine oxidase beta subunit. | 0.922 |
| Atu4221 | soxD | Atu4221 | Atu4068 | Conserved hypothetical protein. | Sarcosine oxidase delta subunit. | 0.970 |
| Atu4221 | soxD-2 | Atu4221 | Atu4223 | Conserved hypothetical protein. | Sarcosine oxidase delta subunit. | 0.955 |
| Atu4221 | soxD-3 | Atu4221 | Atu4311 | Conserved hypothetical protein. | Sarcosine oxidase delta subunit. | 0.970 |
| Atu4221 | soxG | Atu4221 | Atu4070 | Conserved hypothetical protein. | Sarcosine oxidase gamma subunit. | 0.900 |
| Atu4221 | soxG-2 | Atu4221 | Atu4313 | Conserved hypothetical protein. | Sarcosine oxidase gamma subunit. | 0.900 |
| gcvP | Atu4221 | Atu1462 | Atu4221 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Conserved hypothetical protein. | 0.907 |
| gcvP | glyA-2 | Atu1462 | Atu4314 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.998 |
| gcvP | soxA-3 | Atu1462 | Atu4312 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase alpha subunit. | 0.999 |
| gcvP | soxB | Atu1462 | Atu4066 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase beta subunit. | 0.911 |
| gcvP | soxB-3 | Atu1462 | Atu4310 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase beta subunit. | 0.911 |
| gcvP | soxD | Atu1462 | Atu4068 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase delta subunit. | 0.903 |
| gcvP | soxD-3 | Atu1462 | Atu4311 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase delta subunit. | 0.903 |
| gcvP | soxG | Atu1462 | Atu4070 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase gamma subunit. | 0.907 |
| gcvP | soxG-2 | Atu1462 | Atu4313 | Glycine cleavage system protein P2; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Sarcosine oxidase gamma subunit. | 0.907 |
| glyA-2 | Atu4221 | Atu4314 | Atu4221 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Conserved hypothetical protein. | 0.906 |