| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Atu1632 | glyA-2 | Atu1632 | Atu4314 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.563 |
| Atu1632 | soxA | Atu1632 | Atu4069 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase alpha subunit. | 0.981 |
| Atu1632 | soxA-2 | Atu1632 | Atu4222 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase alpha subunit. | 0.823 |
| Atu1632 | soxA-3 | Atu1632 | Atu4312 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase alpha subunit. | 0.980 |
| Atu1632 | soxB | Atu1632 | Atu4066 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase beta subunit. | 0.936 |
| Atu1632 | soxB-3 | Atu1632 | Atu4310 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase beta subunit. | 0.935 |
| Atu1632 | soxD | Atu1632 | Atu4068 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase delta subunit. | 0.990 |
| Atu1632 | soxD-3 | Atu1632 | Atu4311 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase delta subunit. | 0.988 |
| Atu1632 | soxG | Atu1632 | Atu4070 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase gamma subunit. | 0.980 |
| Atu1632 | soxG-2 | Atu1632 | Atu4313 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase gamma subunit. | 0.972 |
| glyA-2 | Atu1632 | Atu4314 | Atu1632 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.563 |
| glyA-2 | soxA | Atu4314 | Atu4069 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Sarcosine oxidase alpha subunit. | 0.969 |
| glyA-2 | soxA-2 | Atu4314 | Atu4222 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Sarcosine oxidase alpha subunit. | 0.709 |
| glyA-2 | soxA-3 | Atu4314 | Atu4312 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Sarcosine oxidase alpha subunit. | 0.991 |
| glyA-2 | soxB | Atu4314 | Atu4066 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Sarcosine oxidase beta subunit. | 0.903 |
| glyA-2 | soxB-3 | Atu4314 | Atu4310 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Sarcosine oxidase beta subunit. | 0.953 |
| glyA-2 | soxD | Atu4314 | Atu4068 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Sarcosine oxidase delta subunit. | 0.906 |
| glyA-2 | soxD-3 | Atu4314 | Atu4311 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Sarcosine oxidase delta subunit. | 0.972 |
| glyA-2 | soxG | Atu4314 | Atu4070 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Sarcosine oxidase gamma subunit. | 0.906 |
| glyA-2 | soxG-2 | Atu4314 | Atu4313 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Sarcosine oxidase gamma subunit. | 0.972 |