node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atu3364 | Atu4684 | Atu3364 | Atu4684 | D-amino acid dehydrogenase. | Conserved hypothetical protein; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Can also catalyze the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4- hydroxy-D-proline (c4DHyp), albeit with 30-fold lower efficiency. Is likely involved in both degradation pathways that convert t3LHyp to L- proline and t4LHyp to alpha-ketoglutarate, which would allow A.tumefaciens to grow on t3LHyp or t4LHyp as a sole carbon source. Displays no proline racemase activity. | 0.688 |
Atu3364 | dadA-2 | Atu3364 | Atu4682 | D-amino acid dehydrogenase. | D-amino acid dehydrogenase, small subunit. | 0.904 |
Atu3364 | dapA-6 | Atu3364 | Atu4675 | D-amino acid dehydrogenase. | Dihydrodipicolinate synthase; Belongs to the DapA family. | 0.609 |
Atu4676 | Atu4678 | Atu4676 | Atu4678 | Putative malate dehydrogenase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L- proline (t3LHyp) to L-proline, which would allow A.tumefaciens to grow on t3LHyp as a sole carbon source; Belongs to the LDH2/MDH2 oxidoreductase family. | ABC transporter, substrate binding protein (amino acid). | 0.780 |
Atu4676 | Atu4679 | Atu4676 | Atu4679 | Putative malate dehydrogenase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L- proline (t3LHyp) to L-proline, which would allow A.tumefaciens to grow on t3LHyp as a sole carbon source; Belongs to the LDH2/MDH2 oxidoreductase family. | ABC transporter, membrane spanning protein (amino acid). | 0.508 |
Atu4676 | Atu4680 | Atu4676 | Atu4680 | Putative malate dehydrogenase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L- proline (t3LHyp) to L-proline, which would allow A.tumefaciens to grow on t3LHyp as a sole carbon source; Belongs to the LDH2/MDH2 oxidoreductase family. | ABC transporter, membrane spanning protein (amino acid). | 0.497 |
Atu4676 | Atu4681 | Atu4676 | Atu4681 | Putative malate dehydrogenase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L- proline (t3LHyp) to L-proline, which would allow A.tumefaciens to grow on t3LHyp as a sole carbon source; Belongs to the LDH2/MDH2 oxidoreductase family. | ABC transporter, nucleotide binding/ATPase protein (amino acid). | 0.408 |
Atu4676 | Atu4683 | Atu4676 | Atu4683 | Putative malate dehydrogenase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L- proline (t3LHyp) to L-proline, which would allow A.tumefaciens to grow on t3LHyp as a sole carbon source; Belongs to the LDH2/MDH2 oxidoreductase family. | Conserved hypothetical protein. | 0.857 |
Atu4676 | Atu4684 | Atu4676 | Atu4684 | Putative malate dehydrogenase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L- proline (t3LHyp) to L-proline, which would allow A.tumefaciens to grow on t3LHyp as a sole carbon source; Belongs to the LDH2/MDH2 oxidoreductase family. | Conserved hypothetical protein; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Can also catalyze the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4- hydroxy-D-proline (c4DHyp), albeit with 30-fold lower efficiency. Is likely involved in both degradation pathways that convert t3LHyp to L- proline and t4LHyp to alpha-ketoglutarate, which would allow A.tumefaciens to grow on t3LHyp or t4LHyp as a sole carbon source. Displays no proline racemase activity. | 0.718 |
Atu4676 | arcB | Atu4676 | Atu3949 | Putative malate dehydrogenase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L- proline (t3LHyp) to L-proline, which would allow A.tumefaciens to grow on t3LHyp as a sole carbon source; Belongs to the LDH2/MDH2 oxidoreductase family. | Ornithine cyclodeaminase. | 0.468 |
Atu4676 | dadA-2 | Atu4676 | Atu4682 | Putative malate dehydrogenase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L- proline (t3LHyp) to L-proline, which would allow A.tumefaciens to grow on t3LHyp as a sole carbon source; Belongs to the LDH2/MDH2 oxidoreductase family. | D-amino acid dehydrogenase, small subunit. | 0.773 |
Atu4676 | dapA-6 | Atu4676 | Atu4675 | Putative malate dehydrogenase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L- proline (t3LHyp) to L-proline, which would allow A.tumefaciens to grow on t3LHyp as a sole carbon source; Belongs to the LDH2/MDH2 oxidoreductase family. | Dihydrodipicolinate synthase; Belongs to the DapA family. | 0.676 |
Atu4678 | Atu4676 | Atu4678 | Atu4676 | ABC transporter, substrate binding protein (amino acid). | Putative malate dehydrogenase; Catalyzes the reduction of Delta(1)-pyrroline-2-carboxylate (Pyr2C) to L-proline, using NADPH as the electron donor. Is likely involved in a degradation pathway that converts trans-3-hydroxy-L- proline (t3LHyp) to L-proline, which would allow A.tumefaciens to grow on t3LHyp as a sole carbon source; Belongs to the LDH2/MDH2 oxidoreductase family. | 0.780 |
Atu4678 | Atu4679 | Atu4678 | Atu4679 | ABC transporter, substrate binding protein (amino acid). | ABC transporter, membrane spanning protein (amino acid). | 0.983 |
Atu4678 | Atu4680 | Atu4678 | Atu4680 | ABC transporter, substrate binding protein (amino acid). | ABC transporter, membrane spanning protein (amino acid). | 0.982 |
Atu4678 | Atu4681 | Atu4678 | Atu4681 | ABC transporter, substrate binding protein (amino acid). | ABC transporter, nucleotide binding/ATPase protein (amino acid). | 0.980 |
Atu4678 | Atu4683 | Atu4678 | Atu4683 | ABC transporter, substrate binding protein (amino acid). | Conserved hypothetical protein. | 0.814 |
Atu4678 | Atu4684 | Atu4678 | Atu4684 | ABC transporter, substrate binding protein (amino acid). | Conserved hypothetical protein; Catalyzes the dehydration of trans-3-hydroxy-L-proline (t3LHyp) to Delta(1)-pyrroline-2-carboxylate (Pyr2C). Can also catalyze the epimerization of trans-4-hydroxy-L-proline (t4LHyp) to cis-4- hydroxy-D-proline (c4DHyp), albeit with 30-fold lower efficiency. Is likely involved in both degradation pathways that convert t3LHyp to L- proline and t4LHyp to alpha-ketoglutarate, which would allow A.tumefaciens to grow on t3LHyp or t4LHyp as a sole carbon source. Displays no proline racemase activity. | 0.718 |
Atu4678 | dadA-2 | Atu4678 | Atu4682 | ABC transporter, substrate binding protein (amino acid). | D-amino acid dehydrogenase, small subunit. | 0.852 |
Atu4678 | dapA-6 | Atu4678 | Atu4675 | ABC transporter, substrate binding protein (amino acid). | Dihydrodipicolinate synthase; Belongs to the DapA family. | 0.657 |