A3770_03p22370 protein (Chloropicon primus) - STRING interaction network

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second shell of interactors

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filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

A3770_03p22370

Subunit beta of T-complex protein 1. (528 aa)

Predicted Functional Partners:

A3770_01p05280

0.999

A3770_04p30250

0.999

A3770_06p43440

0.999

A3770_13p67790

0.999

A3770_11p64630

0.999

A3770_02p10750

0.993

A3770_03p22810

0.993

A3770_02p17070

0.992

A3770_09p54950

0.992

A3770_02p18120

0.954

Your Current Organism:

Chloropicon primus

NCBI taxonomy Id: 1764295
Other names: C. primus, Chlorophyta sp. CCMP1205, Chloropicon primus Lopes dos Santos & Eikrem, 2017, Coccoid green alga CCMP1205, Prasino-clade-7_X-A2 sp. RCC717, Prasino-clade-7_X-A3 sp. RCC1019, Prasino-clade-7_X-A3 sp. RCC1032, Prasino-clade-7_X-A3 sp. RCC1043, Prasinophyceae sp. CCMP1205, Prasinophyceae sp. RCC1019 (clade 7X-A3), Prasinophyceae sp. RCC1032 (clade 7X-A3), Prasinophyceae sp. RCC1032 (clade VIIA), Prasinophyceae sp. RCC1043 (clade 7X-A3), Prasinophyceae sp. RCC717 (clade 7X-A2), coccoid chlorophyte sp. CCMP1205, coccoid prasinophyte sp. CCMP1205, prasinophyte sp. CCMP1205, prasinophyte sp. NIES-3671, prasinophyte sp. NIES-3671 (clade VIIA3), prasinophyte sp. RCC1019, prasinophyte sp. RCC1019 (clade VIIA3), prasinophyte sp. RCC1032, prasinophyte sp. RCC1032 (clade VIIA), prasinophyte sp. RCC1032 (clade VIIA3), prasinophyte sp. RCC1043, prasinophyte sp. RCC1043 (clade VIIA3), prasinophyte sp. RCC717, prasinophyte sp. RCC717 (clade VIIA2)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A3770_01p05280	A3770_02p10750	A0A5B8MFE3	A0A5B8MDT9	T-complex protein 1 subunit gamma.	Uncharacterized protein.	0.975
A3770_01p05280	A3770_02p17070	A0A5B8MFE3	A0A5B8MFL3	T-complex protein 1 subunit gamma.	Subunit alpha of T-complex protein 1.	0.982
A3770_01p05280	A3770_02p18120	A0A5B8MFE3	A0A5B8MGT5	T-complex protein 1 subunit gamma.	Glutathione S-transferase.	0.792
A3770_01p05280	A3770_03p22370	A0A5B8MFE3	A0A5B8MH17	T-complex protein 1 subunit gamma.	Subunit beta of T-complex protein 1.	0.999
A3770_01p05280	A3770_03p22810	A0A5B8MFE3	A0A5B8MH62	T-complex protein 1 subunit gamma.	T-complex protein 1 subunit delta.	0.976
A3770_01p05280	A3770_04p30250	A0A5B8MFE3	A0A5B8MJA5	T-complex protein 1 subunit gamma.	Subunit epsilon of T-complex protein 1.	0.999
A3770_01p05280	A3770_06p43440	A0A5B8MFE3	A0A5B8MMP3	T-complex protein 1 subunit gamma.	Subunit zeta of t-complex protein 1.	0.999
A3770_01p05280	A3770_09p54950	A0A5B8MFE3	A0A5B8MRS9	T-complex protein 1 subunit gamma.	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	0.982
A3770_01p05280	A3770_11p64630	A0A5B8MFE3	A0A5B8MWC9	T-complex protein 1 subunit gamma.	Subunit theta of T-complex protein 1.	0.999
A3770_01p05280	A3770_13p67790	A0A5B8MFE3	A0A5B8MVB4	T-complex protein 1 subunit gamma.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.999
A3770_02p10750	A3770_01p05280	A0A5B8MDT9	A0A5B8MFE3	Uncharacterized protein.	T-complex protein 1 subunit gamma.	0.975
A3770_02p10750	A3770_02p17070	A0A5B8MDT9	A0A5B8MFL3	Uncharacterized protein.	Subunit alpha of T-complex protein 1.	0.964
A3770_02p10750	A3770_02p18120	A0A5B8MDT9	A0A5B8MGT5	Uncharacterized protein.	Glutathione S-transferase.	0.616
A3770_02p10750	A3770_03p22370	A0A5B8MDT9	A0A5B8MH17	Uncharacterized protein.	Subunit beta of T-complex protein 1.	0.993
A3770_02p10750	A3770_04p30250	A0A5B8MDT9	A0A5B8MJA5	Uncharacterized protein.	Subunit epsilon of T-complex protein 1.	0.991
A3770_02p10750	A3770_06p43440	A0A5B8MDT9	A0A5B8MMP3	Uncharacterized protein.	Subunit zeta of t-complex protein 1.	0.984
A3770_02p10750	A3770_09p54950	A0A5B8MDT9	A0A5B8MRS9	Uncharacterized protein.	Uncharacterized protein; Belongs to the TCP-1 chaperonin family.	0.964
A3770_02p10750	A3770_11p64630	A0A5B8MDT9	A0A5B8MWC9	Uncharacterized protein.	Subunit theta of T-complex protein 1.	0.987
A3770_02p10750	A3770_13p67790	A0A5B8MDT9	A0A5B8MVB4	Uncharacterized protein.	T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.	0.984
A3770_02p17070	A3770_01p05280	A0A5B8MFL3	A0A5B8MFE3	Subunit alpha of T-complex protein 1.	T-complex protein 1 subunit gamma.	0.982

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Network Stats

number of nodes:

11

number of edges:

31

average node degree:

5.64

avg. local clustering coefficient:

0.911

expected number of edges:

10

PPI enrichment p-value:

1.35e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016114

Terpenoid biosynthetic process

8 of 12

2.42

6.7

7.87e-15

GO:0019288

Isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway

7 of 7

2.6

6.7

4.66e-14

GO:0090407

Organophosphate biosynthetic process

8 of 130

1.39

2.15

9.06e-09

GO:0019637

Organophosphate metabolic process

9 of 177

1.3

2.01

1.62e-09

GO:1901135

Carbohydrate derivative metabolic process

9 of 210

1.23

1.77

6.72e-09

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016725

Oxidoreductase activity, acting on CH or CH2 groups

3 of 8

2.17

1.51

0.0013

GO:0051745

4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity

2 of 2

2.6

1.13

0.0086

GO:0051539

4 iron, 4 sulfur cluster binding

3 of 29

1.61

0.99

0.0086

GO:0046872

Metal ion binding

7 of 488

0.75

0.52

0.0086

GO:0043167

Ion binding

9 of 894

0.6

0.43

0.0086

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005829

Cytosol

5 of 250

0.9

0.53

0.0261

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4282

Isoprenoid biosynthetic process

7 of 11

2.4

5.82

8.50e-13

CL:4281

Isoprenoid metabolic process, and Carotenoid biosynthesis

8 of 21

2.18

5.54

2.10e-13

CL:4284

Isoprene biosynthesis

5 of 5

2.6

4.56

1.70e-09

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00900

Terpenoid backbone biosynthesis

8 of 18

2.24

6.19

1.03e-14

map01110

Biosynthesis of secondary metabolites

9 of 542

0.82

0.78

2.19e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0414

Isoprene biosynthesis

8 of 8

2.6

7.82

1.38e-16

KW-0004

4Fe-4S

3 of 25

1.68

1.22

0.0026

KW-0479

Metal-binding

7 of 228

1.08

1.13

3.48e-05

KW-0560

Oxidoreductase

4 of 118

1.13

0.79

0.0069

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02401

LytB protein

2 of 2

2.6

0.91

0.0220

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