A3770_08p52100 protein (Chloropicon primus) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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Score

A3770_08p52100

Heme peroxidase. (980 aa)

Predicted Functional Partners:

A3770_02p12030

0.588

A3770_08p53130

0.564

A3770_03p20160

0.563

A3770_13p68940

0.563

A3770_14p71650

0.549

A3770_09p55990

0.486

A3770_12p67100

0.486

A3770_04p31190

0.446

A3770_09p54710

0.446

Your Current Organism:

Chloropicon primus

NCBI taxonomy Id: 1764295
Other names: C. primus, Chlorophyta sp. CCMP1205, Chloropicon primus Lopes dos Santos & Eikrem, 2017, Coccoid green alga CCMP1205, Prasino-clade-7_X-A2 sp. RCC717, Prasino-clade-7_X-A3 sp. RCC1019, Prasino-clade-7_X-A3 sp. RCC1032, Prasino-clade-7_X-A3 sp. RCC1043, Prasinophyceae sp. CCMP1205, Prasinophyceae sp. RCC1019 (clade 7X-A3), Prasinophyceae sp. RCC1032 (clade 7X-A3), Prasinophyceae sp. RCC1032 (clade VIIA), Prasinophyceae sp. RCC1043 (clade 7X-A3), Prasinophyceae sp. RCC717 (clade 7X-A2), coccoid chlorophyte sp. CCMP1205, coccoid prasinophyte sp. CCMP1205, prasinophyte sp. CCMP1205, prasinophyte sp. NIES-3671, prasinophyte sp. NIES-3671 (clade VIIA3), prasinophyte sp. RCC1019, prasinophyte sp. RCC1019 (clade VIIA3), prasinophyte sp. RCC1032, prasinophyte sp. RCC1032 (clade VIIA), prasinophyte sp. RCC1032 (clade VIIA3), prasinophyte sp. RCC1043, prasinophyte sp. RCC1043 (clade VIIA3), prasinophyte sp. RCC717, prasinophyte sp. RCC717 (clade VIIA2)

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A3770_02p12030	A3770_03p20160	A0A5B8MG96	A0A5B8MFQ5	Cytochrome P450 sterol 14-demethylase; Belongs to the cytochrome P450 family.	Glutathione S-transferase.	0.662
A3770_02p12030	A3770_08p52100	A0A5B8MG96	A0A5B8MTG2	Cytochrome P450 sterol 14-demethylase; Belongs to the cytochrome P450 family.	Heme peroxidase.	0.588
A3770_02p12030	A3770_14p71650	A0A5B8MG96	A0A5B8MW36	Cytochrome P450 sterol 14-demethylase; Belongs to the cytochrome P450 family.	HSP20-like chaperone.	0.669
A3770_03p20160	A3770_02p12030	A0A5B8MFQ5	A0A5B8MG96	Glutathione S-transferase.	Cytochrome P450 sterol 14-demethylase; Belongs to the cytochrome P450 family.	0.662
A3770_03p20160	A3770_08p52100	A0A5B8MFQ5	A0A5B8MTG2	Glutathione S-transferase.	Heme peroxidase.	0.563
A3770_03p20160	A3770_14p71650	A0A5B8MFQ5	A0A5B8MW36	Glutathione S-transferase.	HSP20-like chaperone.	0.794
A3770_04p31190	A3770_08p52100	A0A5B8MJZ3	A0A5B8MTG2	Glycoside hydrolase.	Heme peroxidase.	0.446
A3770_04p31190	A3770_09p55990	A0A5B8MJZ3	A0A5B8MRP7	Glycoside hydrolase.	Aspartate aminotransferase.	0.453
A3770_04p31190	A3770_12p67100	A0A5B8MJZ3	A0A5B8MX84	Glycoside hydrolase.	Aspartate aminotransferase.	0.453
A3770_04p31190	A3770_13p68940	A0A5B8MJZ3	A0A5B8MVV0	Glycoside hydrolase.	Aromatic amino acid hydroxylase.	0.557
A3770_08p52100	A3770_02p12030	A0A5B8MTG2	A0A5B8MG96	Heme peroxidase.	Cytochrome P450 sterol 14-demethylase; Belongs to the cytochrome P450 family.	0.588
A3770_08p52100	A3770_03p20160	A0A5B8MTG2	A0A5B8MFQ5	Heme peroxidase.	Glutathione S-transferase.	0.563
A3770_08p52100	A3770_04p31190	A0A5B8MTG2	A0A5B8MJZ3	Heme peroxidase.	Glycoside hydrolase.	0.446
A3770_08p52100	A3770_08p53130	A0A5B8MTG2	A0A5B8MT26	Heme peroxidase.	Heat shock protein Hsp70; Belongs to the heat shock protein 70 family.	0.564
A3770_08p52100	A3770_09p54710	A0A5B8MTG2	A0A5B8MR89	Heme peroxidase.	Putative chitinase.	0.446
A3770_08p52100	A3770_09p55990	A0A5B8MTG2	A0A5B8MRP7	Heme peroxidase.	Aspartate aminotransferase.	0.486
A3770_08p52100	A3770_12p67100	A0A5B8MTG2	A0A5B8MX84	Heme peroxidase.	Aspartate aminotransferase.	0.486
A3770_08p52100	A3770_13p68940	A0A5B8MTG2	A0A5B8MVV0	Heme peroxidase.	Aromatic amino acid hydroxylase.	0.563
A3770_08p52100	A3770_14p71650	A0A5B8MTG2	A0A5B8MW36	Heme peroxidase.	HSP20-like chaperone.	0.549
A3770_08p53130	A3770_08p52100	A0A5B8MT26	A0A5B8MTG2	Heat shock protein Hsp70; Belongs to the heat shock protein 70 family.	Heme peroxidase.	0.564

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

10

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009097

Isoleucine biosynthetic process

7 of 14

2.26

5.34

2.79e-12

GO:0009099

Valine biosynthetic process

5 of 10

2.26

3.86

1.31e-08

GO:1901607

Alpha-amino acid biosynthetic process

10 of 104

1.55

3.16

1.07e-12

GO:0046394

Carboxylic acid biosynthetic process

11 of 166

1.39

2.55

1.07e-12

GO:0043650

Dicarboxylic acid biosynthetic process

3 of 19

1.76

1.4

0.0012

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000287

Magnesium ion binding

5 of 65

1.45

1.34

0.00046

GO:0019842

Vitamin binding

4 of 46

1.5

1.14

0.0026

GO:0015930

Glutamate synthase activity

2 of 2

2.56

1.12

0.0090

GO:0004455

Ketol-acid reductoisomerase activity

2 of 2

2.56

1.12

0.0090

GO:0050661

NADP binding

3 of 22

1.7

1.01

0.0090

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005948

Acetolactate synthase complex

2 of 2

2.56

1.39

0.0028

GO:0005829

Cytosol

7 of 324

0.9

0.76

0.00080

GO:0005737

Cytoplasm

9 of 1245

0.42

0.29

0.0348

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:993

Branched-chain amino acid metabolic process

6 of 23

1.98

3.5

1.00e-08

CL:924

Branched-chain amino acid metabolic process, and Aspartate family amino acid biosynthetic process

8 of 58

1.7

3.32

2.20e-10

CL:923

Alpha-amino acid biosynthetic process, and Dicarboxylic acid metabolic process

9 of 84

1.59

3.09

5.47e-11

CL:996

Branched-chain amino acid metabolic process

4 of 17

1.94

2.12

3.68e-05

CL:810

Glutamate biosynthetic process, and Ammonia ligase activity

2 of 5

2.17

0.87

0.0239

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00290

Valine, leucine and isoleucine biosynthesis

7 of 22

2.07

4.63

1.56e-11

map00770

Pantothenate and CoA biosynthesis

6 of 21

2.02

3.94

8.68e-10

map01210

2-Oxocarboxylic acid metabolism

6 of 51

1.63

2.58

7.73e-08

map01230

Biosynthesis of amino acids

10 of 159

1.36

2.38

1.56e-11

map00660

C5-Branched dibasic acid metabolism

2 of 10

1.87

1.09

0.0074

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005948

Acetolactate synthase complex

2 of 4

2.26

1.07

0.0102

GOCC:0005737

Cytoplasm

10 of 946

0.59

0.47

0.0014

GOCC:0005622

Intracellular

11 of 1345

0.48

0.39

0.0014

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0100

Branched-chain amino acid biosynthesis

4 of 14

2.02

2.3

1.87e-05

KW-0412

Isoleucine biosynthesis

2 of 3

2.39

1.26

0.0047

KW-0663

Pyridoxal phosphate

3 of 40

1.44

0.92

0.0091

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04898

Glutamate synthase central domain

2 of 2

2.56

0.85

0.0286

PF02776

Thiamine pyrophosphate enzyme, N-terminal TPP binding domain

2 of 2

2.56

0.85

0.0286

PF01645

Conserved region in glutamate synthase

2 of 2

2.56

0.85

0.0286

PF01493

GXGXG motif

2 of 2

2.56

0.85

0.0286

PF01450

Acetohydroxy acid isomeroreductase, catalytic domain

2 of 2

2.56

0.85

0.0286

(more ...)

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