A3770_15p73650 protein (Chloropicon primus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A3770_15p73650

Acyl-CoA-binding domain-containing protein. (369 aa)

Predicted Functional Partners:

A3770_05p35630

0.627

A3770_18p80900

0.593

A3770_15p75920

0.592

A3770_11p61530

0.588

A3770_12p65150

0.561

A3770_02p11130

0.554

A3770_04p28270

0.548

A3770_01p01070

0.547

A3770_07p50010

0.547

A3770_04p29190

0.546

Your Current Organism:

Chloropicon primus

NCBI taxonomy Id: 1764295
Other names: C. primus, Chlorophyta sp. CCMP1205, Chloropicon primus Lopes dos Santos & Eikrem, 2017, Coccoid green alga CCMP1205, Prasino-clade-7_X-A2 sp. RCC717, Prasino-clade-7_X-A3 sp. RCC1019, Prasino-clade-7_X-A3 sp. RCC1032, Prasino-clade-7_X-A3 sp. RCC1043, Prasinophyceae sp. CCMP1205, Prasinophyceae sp. RCC1019 (clade 7X-A3), Prasinophyceae sp. RCC1032 (clade 7X-A3), Prasinophyceae sp. RCC1032 (clade VIIA), Prasinophyceae sp. RCC1043 (clade 7X-A3), Prasinophyceae sp. RCC717 (clade 7X-A2), coccoid chlorophyte sp. CCMP1205, coccoid prasinophyte sp. CCMP1205, prasinophyte sp. CCMP1205, prasinophyte sp. NIES-3671, prasinophyte sp. NIES-3671 (clade VIIA3), prasinophyte sp. RCC1019, prasinophyte sp. RCC1019 (clade VIIA3), prasinophyte sp. RCC1032, prasinophyte sp. RCC1032 (clade VIIA), prasinophyte sp. RCC1032 (clade VIIA3), prasinophyte sp. RCC1043, prasinophyte sp. RCC1043 (clade VIIA3), prasinophyte sp. RCC717, prasinophyte sp. RCC717 (clade VIIA2)

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A3770_01p01070	A3770_02p11130	A0A5B8MBI9	A0A5B8MG07	Peroxisome biogenesis protein 19.	Uncharacterized protein.	0.999
A3770_01p01070	A3770_04p28270	A0A5B8MBI9	A0A5B8MIU6	Peroxisome biogenesis protein 19.	Peroxisomal targeting signal 1 receptor.	0.667
A3770_01p01070	A3770_04p29190	A0A5B8MBI9	A0A5B8MJE6	Peroxisome biogenesis protein 19.	Peroxisome biogenesis protein.	0.956
A3770_01p01070	A3770_07p50010	A0A5B8MBI9	A0A5B8MPY6	Peroxisome biogenesis protein 19.	Uncharacterized protein.	0.828
A3770_01p01070	A3770_15p73650	A0A5B8MBI9	A0A5B8MWL2	Peroxisome biogenesis protein 19.	Acyl-CoA-binding domain-containing protein.	0.547
A3770_01p01070	A3770_18p80900	A0A5B8MBI9	A0A5B8N0L7	Peroxisome biogenesis protein 19.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.429
A3770_02p11130	A3770_01p01070	A0A5B8MG07	A0A5B8MBI9	Uncharacterized protein.	Peroxisome biogenesis protein 19.	0.999
A3770_02p11130	A3770_04p28270	A0A5B8MG07	A0A5B8MIU6	Uncharacterized protein.	Peroxisomal targeting signal 1 receptor.	0.659
A3770_02p11130	A3770_04p29190	A0A5B8MG07	A0A5B8MJE6	Uncharacterized protein.	Peroxisome biogenesis protein.	0.934
A3770_02p11130	A3770_07p50010	A0A5B8MG07	A0A5B8MPY6	Uncharacterized protein.	Uncharacterized protein.	0.785
A3770_02p11130	A3770_15p73650	A0A5B8MG07	A0A5B8MWL2	Uncharacterized protein.	Acyl-CoA-binding domain-containing protein.	0.554
A3770_04p28270	A3770_01p01070	A0A5B8MIU6	A0A5B8MBI9	Peroxisomal targeting signal 1 receptor.	Peroxisome biogenesis protein 19.	0.667
A3770_04p28270	A3770_02p11130	A0A5B8MIU6	A0A5B8MG07	Peroxisomal targeting signal 1 receptor.	Uncharacterized protein.	0.659
A3770_04p28270	A3770_04p29190	A0A5B8MIU6	A0A5B8MJE6	Peroxisomal targeting signal 1 receptor.	Peroxisome biogenesis protein.	0.979
A3770_04p28270	A3770_05p35630	A0A5B8MIU6	A0A5B8MN56	Peroxisomal targeting signal 1 receptor.	SCP2 domain-containing protein.	0.999
A3770_04p28270	A3770_11p61530	A0A5B8MIU6	A0A5B8MVF4	Peroxisomal targeting signal 1 receptor.	Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.770
A3770_04p28270	A3770_12p65150	A0A5B8MIU6	A0A5B8MUE2	Peroxisomal targeting signal 1 receptor.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.829
A3770_04p28270	A3770_15p73650	A0A5B8MIU6	A0A5B8MWL2	Peroxisomal targeting signal 1 receptor.	Acyl-CoA-binding domain-containing protein.	0.548
A3770_04p28270	A3770_15p75920	A0A5B8MIU6	A0A5B8N032	Peroxisomal targeting signal 1 receptor.	Acetyl-CoA acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family.	0.836
A3770_04p28270	A3770_18p80900	A0A5B8MIU6	A0A5B8N0L7	Peroxisomal targeting signal 1 receptor.	Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family.	0.901

page 1 of 4

Network Stats

number of nodes:

5

number of edges:

8

average node degree:

3.2

avg. local clustering coefficient:

0.667

expected number of edges:

4

PPI enrichment p-value:

0.0502

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042128

Nitrate assimilation

3 of 17

2.47

1.67

0.00079

GO:0034975

Protein folding in endoplasmic reticulum

2 of 8

2.63

1.04

0.0130

GO:0006790

Sulfur compound metabolic process

4 of 279

1.38

0.84

0.0130

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043546

Molybdopterin cofactor binding

7 of 10

3.07

8.55

9.87e-17

GO:0030151

Molybdenum ion binding

7 of 20

2.77

7.56

2.25e-15

GO:0016670

Oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor

6 of 12

2.93

6.87

1.17e-13

GO:0008482

Sulfite oxidase activity

4 of 4

3.23

4.83

1.56e-09

GO:0020037

Heme binding

7 of 162

1.86

3.63

6.79e-10

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005758

Mitochondrial intermembrane space

4 of 75

1.96

1.95

9.88e-05

GO:0031967

Organelle envelope

5 of 785

1.03

0.64

0.0172

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:21707

Sulfide oxidation to sulfate

4 of 12

2.75

3.45

3.79e-07

CL:21208

Nitrate reductase (NADPH) activity

3 of 5

3.01

2.84

6.80e-06

CL:13456

Mixed, incl. Protein disulfide isomerase activity, and Amino-acid transport

3 of 23

2.34

2.03

0.00014

CL:21719

Sulfide oxidation to sulfate

2 of 6

2.75

1.54

0.0016

CL:21708

Sulfide oxidation to sulfate

2 of 6

2.75

1.54

0.0016

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00920

Sulfur metabolism

4 of 70

1.99

2.36

1.16e-05

map00910

Nitrogen metabolism

3 of 92

1.74

1.34

0.0016

map04141

Protein processing in endoplasmic reticulum

4 of 334

1.31

1.07

0.0017

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1614517

Sulfide oxidation to sulfate

4 of 13

2.72

3.64

1.57e-07

MAP-1614558

Degradation of cysteine and homocysteine

4 of 28

2.38

3.06

1.18e-06

MAP-1614635

Sulfur amino acid metabolism

4 of 50

2.13

2.56

6.87e-06

MAP-264876

Insulin processing

2 of 23

2.17

0.88

0.0237

MAP-71291

Metabolism of amino acids and derivatives

4 of 518

1.12

0.6

0.0346

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0274

FAD

5 of 106

1.9

2.71

8.76e-07

KW-0534

Nitrate assimilation

2 of 6

2.75

1.69

0.00084

KW-0500

Molybdenum

2 of 6

2.75

1.69

0.00084

KW-1015

Disulfide bond

2 of 49

1.84

0.85

0.0226

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03404

Mo-co oxidoreductase dimerisation domain

7 of 8

3.17

8.84

3.84e-17

PF00174

Oxidoreductase molybdopterin binding domain

7 of 8

3.17

8.84

3.84e-17

PF00970

Oxidoreductase FAD-binding domain

3 of 13

2.59

2.21

7.92e-05

PF00175

Oxidoreductase NAD-binding domain

3 of 26

2.29

1.8

0.00039

PF04137

Endoplasmic Reticulum Oxidoreductin 1 (ERO1)

2 of 2

3.23

1.64

0.0011

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036374

Oxidoreductase, molybdopterin-binding domain superfamily

7 of 8

3.17

8.62

1.03e-16

IPR008335

Eukaryotic molybdopterin oxidoreductase

7 of 8

3.17

8.62

1.03e-16

IPR000572

Oxidoreductase, molybdopterin-binding domain

7 of 8

3.17

8.62

1.03e-16

IPR005066

Moybdenum cofactor oxidoreductase, dimerisation

6 of 7

3.16

7.36

2.56e-14

IPR014756

Immunoglobulin E-set

7 of 39

2.48

6.26

1.71e-13

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01117

Cytochrome b5-like Heme/Steroid binding domain

3 of 41

2.09

1.53

0.0011

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2024

Credits

Access

Info

About