STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKQ99905.1Isoniazid inducible protein IniB. (389 aa)    
Predicted Functional Partners:
AKQ99906.1
Hypothetical protein.
      0.870
AKQ99908.1
Isoniazid inducible protein IniC.
  
  
 0.772
AKQ99904.1
Hypothetical protein.
     
 0.535
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.473
AKQ99907.1
Isoniazid inducible protein IniA.
       0.471
AKR00530.1
Outer membrane protein A ompA.
  
 
 0.415
AKR01486.1
Hypothetical protein.
  
 
 0.415
AKR01560.1
Hypothetical protein.
   
 
 0.406
AKR02547.1
Membrane protein.
   
 
 0.406
AKR03596.1
Protease.
   
 
 0.406
Your Current Organism:
Mycobacterium tuberculosis variant bovis
NCBI taxonomy Id: 1765
Other names: ATCC 19210, CIP 105234, M. tuberculosis variant bovis, Mycobacterium bovis, Mycobacterium bovis subsp. bovis, Mycobacterium tuberculosis typus bovinus, Mycobacterium tuberculosis var. bovis, NCTC 10772
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.