STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKR01271.1Antitoxin VapB11. (72 aa)    
Predicted Functional Partners:
vapC-16
Ribonuclease; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
 
 0.996
vapC-11
Ribonuclease VapC31; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
      
 0.730
vapC-21
Ribonuclease VapC38; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
      
 0.718
ilvA
L-threonine dehydratase biosynthetic IlvA; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
       0.659
vapC-15
Ribonuclease; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
  
 0.617
cobB
NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
   
    0.603
vapC-19
Ribonuclease; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family.
  
  
 0.576
AKR01720.1
Antitoxin.
  
    0.566
AKR01100.1
Transcriptional regulator.
   
    0.565
AKR01269.1
Deazaflavin-dependent nitroreductase.
       0.565
Your Current Organism:
Mycobacterium tuberculosis variant bovis
NCBI taxonomy Id: 1765
Other names: ATCC 19210, CIP 105234, M. tuberculosis variant bovis, Mycobacterium bovis, Mycobacterium bovis subsp. bovis, Mycobacterium tuberculosis typus bovinus, Mycobacterium tuberculosis var. bovis, NCTC 10772
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