STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKR01574.1MerR family transcriptional regulator. (247 aa)    
Predicted Functional Partners:
AKR01573.1
Glycogen accumulation regulator GarA.
 
    0.913
AKR02625.1
DtxR family transcriptional regulator.
  
  
 0.825
AKR01575.1
Hypothetical protein.
     
 0.823
AKR01576.1
Transcriptional regulator.
 
   
 0.767
AKR01032.1
Transcriptional regulator.
   
  
 0.722
gcvH
Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
       0.696
AKR01570.1
Membrane protein.
       0.692
AKQ99917.1
Chaperone protein DnaJ 1.
  
 
 0.661
AKR01569.1
Hypothetical protein.
       0.661
dnaJ
Chaperone protein DnaJ 2; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
  
 
 0.661
Your Current Organism:
Mycobacterium tuberculosis variant bovis
NCBI taxonomy Id: 1765
Other names: ATCC 19210, CIP 105234, M. tuberculosis variant bovis, Mycobacterium bovis, Mycobacterium bovis subsp. bovis, Mycobacterium tuberculosis typus bovinus, Mycobacterium tuberculosis var. bovis, NCTC 10772
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.