STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKR02084.1Cutinase; Catalyzes the hydrolysis of cutin, a polyester that forms the structure of plant cuticle. (230 aa)    
Predicted Functional Partners:
AKR01371.1
PE-PGRS family protein.
 
 
 0.785
glyA-2
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 
 0.691
AKQ99845.1
ESX-3 secretion system protein EccA3.
  
 
 0.690
AKQ99853.1
ESX-3 secretion system protein EccD3.
  
   
 0.660
AKR00970.1
Hypothetical protein.
  
  
  0.655
AKQ99704.1
Phosphotyrosine protein phosphatase.
   
 
 0.640
AKR01540.1
ESX-5 secretion system protein EccA5.
  
 
 0.640
AKR03037.1
NADH-quinone oxidoreductase subunit M.
    
 
 0.638
AKR03836.1
ESX-2 secretion system protein EccA2.
  
 
 0.623
AKR00969.1
Hypothetical protein.
  
 
  0.614
Your Current Organism:
Mycobacterium tuberculosis variant bovis
NCBI taxonomy Id: 1765
Other names: ATCC 19210, CIP 105234, M. tuberculosis variant bovis, Mycobacterium bovis, Mycobacterium bovis subsp. bovis, Mycobacterium tuberculosis typus bovinus, Mycobacterium tuberculosis var. bovis, NCTC 10772
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