STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKR02541.1Pyridine nucleotide-disulfide oxidoreductase. (471 aa)    
Predicted Functional Partners:
AKR00938.1
Multifunctional 2-oxoglutarate metabolism enzyme.
 
 0.997
AKQ99708.1
NAD(P) transhydrogenase subunit alpha.
     
 0.952
AKQ99709.1
NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
   
 
 0.935
AKR02251.1
Glutamine-dependent NAD(+) synthetase.
    
 0.931
AKR01993.1
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 0.930
AKQ99707.1
NAD(P) transhydrogenase subunit alpha.
     
 0.927
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.926
cobB
NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
  
 0.925
AKR02315.1
2-oxoisovalerate dehydrogenase subunit beta.
 
 0.924
AKR03092.1
NADH pyrophosphatase.
     
 0.904
Your Current Organism:
Mycobacterium tuberculosis variant bovis
NCBI taxonomy Id: 1765
Other names: ATCC 19210, CIP 105234, M. tuberculosis variant bovis, Mycobacterium bovis, Mycobacterium bovis subsp. bovis, Mycobacterium tuberculosis typus bovinus, Mycobacterium tuberculosis var. bovis, NCTC 10772
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