STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKR02547.1Membrane protein. (165 aa)    
Predicted Functional Partners:
lexA
Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.770
nrdR
Transcriptional repressor NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
  
    0.748
AKR02545.1
Hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands.
     
 0.601
AKR01193.1
Peptidoglycan endopeptidase RipA.
  
  
 0.430
AKR00530.1
Outer membrane protein A ompA.
  
 
 0.428
AKR01486.1
Hypothetical protein.
  
 
 0.428
AKR01194.1
Peptidoglycan endopeptidase RipB.
  
  
 0.422
AKQ99904.1
Hypothetical protein.
   
 
 0.406
AKQ99905.1
Isoniazid inducible protein IniB.
   
 
 0.406
AKQ99906.1
Hypothetical protein.
   
 
 0.406
Your Current Organism:
Mycobacterium tuberculosis variant bovis
NCBI taxonomy Id: 1765
Other names: ATCC 19210, CIP 105234, M. tuberculosis variant bovis, Mycobacterium bovis, Mycobacterium bovis subsp. bovis, Mycobacterium tuberculosis typus bovinus, Mycobacterium tuberculosis var. bovis, NCTC 10772
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.