STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OPG17386.12-oxoglutarate dehydrogenase E1 component; Derived by automated computational analysis using gene prediction method: Protein Homology. (863 aa)    
Predicted Functional Partners:
OPG17387.1
Dihydrolipoamide succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
OPG16313.1
Dienelactone hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.996
OPG15722.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.996
OPG16312.1
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.987
OPG15526.1
Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.977
merA
mercury(II) reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.972
sucC
succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.959
OPG17124.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.927
gcvH
Glycine cleavage system protein H; Is also involved in protein lipoylation via its role as an octanoyl/lipoyl carrier protein intermediate; Belongs to the GcvH family.
   
 
 0.909
sdhA
Succinate dehydrogenase flavoprotein subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.898
Your Current Organism:
Acidibacillus ferrooxidans
NCBI taxonomy Id: 1765683
Other names: A. ferrooxidans, Alicyclobacillaceae bacterium ITV01, Alicyclobacillaceae bacterium SLC40, Firmicutes bacterium BSH1, Firmicutes bacterium MCF99, Gram-positive iron-oxidizing acidophile G1, Gram-positive iron-oxidizing acidophile SLC66, bacterium GS1, strain SLC66
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.