APZ44596.1 protein (Acidihalobacter ferrooxidans)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

APZ44596.1

Bacitracin ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)

Predicted Functional Partners:

APZ42883.1

0.996

APZ42882.1

0.995

APZ44595.1

0.988

APZ42886.1

0.985

APZ43746.1

0.890

APZ44527.1

0.840

APZ43942.1

0.825

APZ42884.1

0.763

APZ43743.1

0.720

APZ44766.1

0.680

Your Current Organism:

Acidihalobacter ferrooxidans

NCBI taxonomy Id: 1765967
Other names: A. ferrooxidans

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42882.1	APZ42883.1	BW247_07065	BW247_07080	Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nitrate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.935
APZ42882.1	APZ42884.1	BW247_07065	BW247_07085	Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nitrite reductase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	0.813
APZ42882.1	APZ42886.1	BW247_07065	BW247_07095	Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.	0.955
APZ42882.1	APZ43743.1	BW247_07065	BW247_12145	Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.545
APZ42882.1	APZ43746.1	BW247_07065	BW247_12160	Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.679
APZ42882.1	APZ44595.1	BW247_07065	BW247_07070	Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nitrate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
APZ42882.1	APZ44596.1	BW247_07065	BW247_07075	Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bacitracin ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.995
APZ42882.1	APZ44766.1	BW247_07065	BW247_15775	Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.496
APZ42883.1	APZ42882.1	BW247_07080	BW247_07065	Nitrate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.935
APZ42883.1	APZ42884.1	BW247_07080	BW247_07085	Nitrate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nitrite reductase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	0.956
APZ42883.1	APZ42886.1	BW247_07080	BW247_07095	Nitrate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.	0.986
APZ42883.1	APZ43743.1	BW247_07080	BW247_12145	Nitrate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.545
APZ42883.1	APZ43746.1	BW247_07080	BW247_12160	Nitrate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.688
APZ42883.1	APZ44595.1	BW247_07080	BW247_07070	Nitrate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Nitrate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.997
APZ42883.1	APZ44596.1	BW247_07080	BW247_07075	Nitrate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bacitracin ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.996
APZ42883.1	APZ44766.1	BW247_07080	BW247_15775	Nitrate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.496
APZ42884.1	APZ42882.1	BW247_07085	BW247_07065	Nitrite reductase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	Nitrate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.813
APZ42884.1	APZ42883.1	BW247_07085	BW247_07080	Nitrite reductase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	Nitrate ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.956
APZ42884.1	APZ42886.1	BW247_07085	BW247_07095	Nitrite reductase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	Nitrate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily.	0.999
APZ42884.1	APZ44595.1	BW247_07085	BW247_07070	Nitrite reductase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.	Nitrate ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.740

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.841

expected number of edges:

13

PPI enrichment p-value:

0.00128

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006172

ADP biosynthetic process

2 of 2

3.04

1.56

0.0015

GO:0009179

Purine ribonucleoside diphosphate metabolic process

3 of 19

2.24

1.51

0.0014

GO:0009167

Purine ribonucleoside monophosphate metabolic process

3 of 20

2.22

1.51

0.0014

GO:0032386

Regulation of intracellular transport

3 of 25

2.12

1.49

0.0014

GO:0003400

Regulation of COPII vesicle coating

2 of 4

2.74

1.44

0.0024

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0050145

Nucleoside monophosphate kinase activity

3 of 6

2.74

2.27

6.86e-05

GO:0004017

Adenylate kinase activity

2 of 3

2.87

1.41

0.0028

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6770

Multivesicular body sorting pathway, and Calpain-like thiol protease family.

6 of 31

2.33

4.58

4.21e-10

CL:6820

Calpain-like thiol protease family., and Regulation of COPII vesicle coating

4 of 6

2.87

3.97

4.53e-08

CL:12808

Metabolism of nucleotides, and Biosynthesis of maresins

3 of 56

1.77

1.05

0.0078

CL:6793

Multivesicular body sorting pathway

2 of 10

2.35

0.95

0.0176

CL:12890

Deoxyribonucleotide biosynthetic process, and Nucleoside monophosphate kinase activity

2 of 15

2.17

0.87

0.0245

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04626

Plant-pathogen interaction

2 of 5

2.65

1.62

0.0011

map00230

Purine metabolism

4 of 100

1.65

1.6

0.00023

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-499943

Interconversion of nucleotide di- and triphosphates

3 of 25

2.12

1.46

0.0016

MAP-15869

Metabolism of nucleotides

3 of 68

1.69

0.92

0.0140

MAP-9668328

Sealing of the nuclear envelope (NE) by ESCRT-III

2 of 13

2.23

0.88

0.0239

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0042584

Chromaffin granule membrane

2 of 3

2.87

1.19

0.0071

GOCC:0005935

Cellular bud neck

2 of 18

2.09

0.85

0.0258

GOCC:0043227

Membrane-bounded organelle

9 of 3197

0.49

0.33

0.0258

GOCC:0043229

Intracellular organelle

10 of 4076

0.43

0.3

0.0258

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13207

AAA domain

2 of 2

3.04

1.31

0.0044

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036193

Adenylate kinase, active site lid domain superfamily

2 of 2

3.04

1.06

0.0125

IPR007862

Adenylate kinase, active site lid domain

2 of 2

3.04

1.06

0.0125

IPR006259

Adenylate kinase subfamily

2 of 2

3.04

1.06

0.0125

IPR033690

Adenylate kinase, conserved site

2 of 3

2.87

1.05

0.0125

IPR000850

Adenylate kinase/UMP-CMP kinase

2 of 3

2.87

1.05

0.0125

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00054

EF-hand, calcium binding motif

2 of 15

2.17

0.81

0.0317

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