STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (495 aa)    
Predicted Functional Partners:
APZ42210.1
Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.904
APZ43634.1
Leucyl aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M17 family.
  
  
 
0.903
gshB
Glutathione synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family.
   
 
 0.902
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.892
gshA
Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
 0.885
APZ43250.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.878
APZ42163.1
Deoxynucleoside kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.849
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
  
  0.785
APZ43310.1
Cysteine synthase B; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family.
    
 0.717
APZ44185.1
Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.699
Your Current Organism:
Acidihalobacter ferrooxidans
NCBI taxonomy Id: 1765967
Other names: A. ferrooxidans
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