node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALI26193.1 | ALI27561.1 | XA26_23480 | XA26_37400 | Acetolactate synthase large subunit. | Branched-chain amino acid aminotransferase. | 0.671 |
ALI26193.1 | ilvC | XA26_23480 | XA26_23500 | Acetolactate synthase large subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.998 |
ALI26193.1 | ilvD | XA26_23480 | XA26_01780 | Acetolactate synthase large subunit. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.927 |
ALI26193.1 | ilvN | XA26_23480 | XA26_23490 | Acetolactate synthase large subunit. | Acetolactate synthase small subunit. | 0.999 |
ALI26193.1 | leuA | XA26_23480 | XA26_30430 | Acetolactate synthase large subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.939 |
ALI26193.1 | leuA-2 | XA26_23480 | XA26_56450 | Acetolactate synthase large subunit. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.982 |
ALI26193.1 | leuC | XA26_23480 | XA26_23660 | Acetolactate synthase large subunit. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.739 |
ALI26193.1 | leuD | XA26_23480 | XA26_23670 | Acetolactate synthase large subunit. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.757 |
ALI27561.1 | ALI26193.1 | XA26_37400 | XA26_23480 | Branched-chain amino acid aminotransferase. | Acetolactate synthase large subunit. | 0.671 |
ALI27561.1 | aspC_2 | XA26_37400 | XA26_06330 | Branched-chain amino acid aminotransferase. | Aspartate aminotransferase. | 0.914 |
ALI27561.1 | ilvC | XA26_37400 | XA26_23500 | Branched-chain amino acid aminotransferase. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.893 |
ALI27561.1 | ilvD | XA26_37400 | XA26_01780 | Branched-chain amino acid aminotransferase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.986 |
ALI27561.1 | ilvN | XA26_37400 | XA26_23490 | Branched-chain amino acid aminotransferase. | Acetolactate synthase small subunit. | 0.750 |
ALI27561.1 | leuA | XA26_37400 | XA26_30430 | Branched-chain amino acid aminotransferase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.971 |
ALI27561.1 | leuA-2 | XA26_37400 | XA26_56450 | Branched-chain amino acid aminotransferase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. | 0.971 |
ALI27561.1 | leuC | XA26_37400 | XA26_23660 | Branched-chain amino acid aminotransferase. | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.760 |
ALI27561.1 | leuD | XA26_37400 | XA26_23670 | Branched-chain amino acid aminotransferase. | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.561 |
ALI27561.1 | panB | XA26_37400 | XA26_37640 | Branched-chain amino acid aminotransferase. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.917 |
aspC_2 | ALI27561.1 | XA26_06330 | XA26_37400 | Aspartate aminotransferase. | Branched-chain amino acid aminotransferase. | 0.914 |
aspC_2 | ilvD | XA26_06330 | XA26_01780 | Aspartate aminotransferase. | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. | 0.926 |