STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
citE_2Hydroxymethylglutaryl-CoA lyase; Belongs to the HpcH/HpaI aldolase family. (268 aa)    
Predicted Functional Partners:
ALI27929.1
Oxidase regulatory-like protein.
 
  
 0.991
ALI27930.1
Isovaleryl-CoA dehydrogenase.
 
  
 0.991
ALI27932.1
Methylcrotonyl-CoA carboxylase carboxyl transferase subunit.
  
  
 0.973
ALI27931.1
Methylcrotonyl-CoA carboxylase biotin-containing subunit.
 
  
 0.967
ALI26424.1
Citrate lyase beta chain; Belongs to the HpcH/HpaI aldolase family.
  
  
0.934
ALI28283.1
L-malyl-CoA/beta-methylmalyl-CoA lyase, actinobacterial type; Belongs to the HpcH/HpaI aldolase family.
 
  
 
0.931
ALI27933.1
Transcriptional regulator, TetR family.
 
   
 0.853
egtD
ABC transporter ATP-binding protein; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
      
 0.798
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
     
 0.794
ALI26792.1
Putative membrane protein.
      
 0.788
Your Current Organism:
Mycolicibacterium fortuitum
NCBI taxonomy Id: 1766
Other names: ATCC 6841, CCUG 20994, CIP 104534, DSM 46621, IFO 13159, JCM 6387, M. fortuitum, Mycobacterium fortuitum, Mycobacterium giae, Mycobacterium minetti, NBRC 13159, NCTC 10394
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