STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARG92086.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)    
Predicted Functional Partners:
ARG95654.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.723
ARG92699.1
Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.605
sucC
succinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
    0.560
ARG94534.1
Signal peptidase I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
 
  
 0.548
ARG93009.1
N-acetylmuramoyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.538
secF
Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
   
 0.533
ARG94267.1
ABC transporter permease; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.
 
  
 0.515
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
    0.496
ARG95809.1
Chromosomal replication initiation protein DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family.
 
  
 0.489
ARG91081.1
UDP-N-acetylmuramate--L-alanine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.465
Your Current Organism:
Mycobacterium kansasii
NCBI taxonomy Id: 1768
Other names: ATCC 12478, CIP 104589, DSM 44162, JCM 6379, M. kansasii, NCTC 13024
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.