STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ARG93956.1Homoserine O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AB hydrolase superfamily. MetX family. (383 aa)    
Predicted Functional Partners:
ARG93957.1
Bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
ARG93955.1
SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.973
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
  
 0.965
metB
Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.961
ARG91700.1
Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.952
ARG91953.1
Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.843
ARG95472.1
Threonine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.840
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.840
glyA1
Serine hydroxymethyltransferase; Catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.833
ARG93546.1
CDP-diacylglycerol--serine O-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
  0.823
Your Current Organism:
Mycobacterium kansasii
NCBI taxonomy Id: 1768
Other names: ATCC 12478, CIP 104589, DSM 44162, JCM 6379, M. kansasii, NCTC 13024
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