node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALW87587.1 | mqnA | AUC44_00650 | AUC44_14920 | 4-hydroxybenzoate octaprenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiA prenyltransferase family. | ABC transporter substrate-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.807 |
ALW87587.1 | mqnB | AUC44_00650 | AUC44_11995 | 4-hydroxybenzoate octaprenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiA prenyltransferase family. | Futalosine hydrolase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.758 |
ALW87587.1 | mqnC | AUC44_00650 | AUC44_06185 | 4-hydroxybenzoate octaprenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiA prenyltransferase family. | Dehypoxanthine futalosine cyclase; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.792 |
ALW87587.1 | mqnD | AUC44_00650 | AUC44_04225 | 4-hydroxybenzoate octaprenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiA prenyltransferase family. | 1,4-dihydroxy-6-naphthoate synthase; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.800 |
ALW87587.1 | mqnE | AUC44_00650 | AUC44_14910 | 4-hydroxybenzoate octaprenyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiA prenyltransferase family. | Aminofutalosine synthase MqnE; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.793 |
ALW89477.1 | AUC44_04185 | AUC44_11685 | AUC44_04185 | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2'-5' RNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.952 |
ALW89477.1 | aroC | AUC44_11685 | AUC44_11645 | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.952 |
ALW89477.1 | mqnA | AUC44_11685 | AUC44_14920 | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter substrate-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.805 |
ALW90026.1 | mqnA | AUC44_14915 | AUC44_14920 | DUF4440 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter substrate-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.805 |
ALW90026.1 | mqnE | AUC44_14915 | AUC44_14910 | DUF4440 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminofutalosine synthase MqnE; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.830 |
AUC44_04185 | ALW89477.1 | AUC44_04185 | AUC44_11685 | 2'-5' RNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.952 |
AUC44_04185 | aroC | AUC44_04185 | AUC44_11645 | 2'-5' RNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.999 |
AUC44_04185 | hisC | AUC44_04185 | AUC44_03505 | 2'-5' RNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Histidinol-phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.590 |
AUC44_04185 | mqnA | AUC44_04185 | AUC44_14920 | 2'-5' RNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter substrate-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.807 |
aroC | ALW89477.1 | AUC44_11645 | AUC44_11685 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.952 |
aroC | AUC44_04185 | AUC44_11645 | AUC44_04185 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 2'-5' RNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
aroC | hisC | AUC44_11645 | AUC44_03505 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Histidinol-phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.728 |
aroC | mqnA | AUC44_11645 | AUC44_14920 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | ABC transporter substrate-binding protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.815 |
hisC | AUC44_04185 | AUC44_03505 | AUC44_04185 | Histidinol-phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 2'-5' RNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.590 |
hisC | aroC | AUC44_03505 | AUC44_11645 | Histidinol-phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.728 |