STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OCN05222.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (172 aa)    
Predicted Functional Partners:
OCN03729.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the NAD synthetase family.
 
 
 0.927
OCN06283.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.913
OCN05643.1
Homocysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.857
OCN06216.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the folylpolyglutamate synthase family.
  
 
 0.635
OCN03809.1
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
    
 0.632
pyrD
Dihydroorotate dehydrogenase B catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.622
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
 0.618
hisE
phosphoribosyl-ATP pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.608
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
    
 0.608
OCN03640.1
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.607
Your Current Organism:
Erysipelotrichaceae bacterium MTC7
NCBI taxonomy Id: 1768196
Other names: E. bacterium MTC7
Server load: low (22%) [HD]