Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
co-expression
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[Homology]
Score
sucCSuccinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (387 aa)    
Predicted Functional Partners:
sucD
Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 0.999
kgd
Multifunctional 2-oxoglutarate metabolism enzyme.
 
 0.999
AMO60335.1
Succinate dehydrogenase/Fumarate reductase transmembrane subunit.
  
 
 0.989
sdhB
Succinate dehydrogenase iron-sulfur subunit.
 
 0.987
AMO60334.1
Succinate dehydrogenase/Fumarate reductase transmembrane subunit.
  
 
 0.985
sdhA_1
Succinate dehydrogenase flavoprotein subunit.
 
 0.984
korA
2-oxoglutarate oxidoreductase subunit KorA.
    
 0.981
frdB
Fumarate reductase iron-sulfur subunit.
 
 0.980
AMO63898.1
Hypothetical protein.
  
 0.978
sdhA_2
Succinate dehydrogenase flavoprotein subunit.
 
 0.976
Your Current Organism:
Mycolicibacterium phlei
NCBI taxonomy Id: 1771
Other names: ATCC 11758, Bacterium phlei, CCUG 21000, CIP 105389, DSM 43239, JCM 5865, JCM 6385, M. phlei, Mycobacterium phlei, NCTC 8151, NRRL B-14615, Sclerothrix phlei
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