STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dhbE2,3-dihydroxybenzoate-AMP ligase. (554 aa)    
Predicted Functional Partners:
mbtB_2
Phenyloxazoline synthase MbtB.
 
 
0.997
AMO62279.1
MbtH-like protein.
 
  
 0.952
dhbC
Isochorismate synthase DhbC.
 
  
 0.940
eryA_2
Erythronolide synthase, modules 1 and 2.
  
 0.935
ppsA_1
Phthiocerol/phenolphthiocerol synthesis polyketide synthase type I PpsA.
 
  
 0.928
trpE
Anthranilate synthase component 1; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
 
  
 0.928
AMO62280.1
Hypothetical protein.
 
  
 0.883
mbtB_1
Phenyloxazoline synthase MbtB.
 
  
 0.865
AMO59698.1
Hypothetical protein.
  
  
 0.852
pks2
Phthioceranic/hydroxyphthioceranic acid synthase.
 
 0.812
Your Current Organism:
Mycolicibacterium phlei
NCBI taxonomy Id: 1771
Other names: ATCC 11758, Bacterium phlei, CCUG 21000, CIP 105389, DSM 43239, JCM 5865, JCM 6385, M. phlei, Mycobacterium phlei, NCTC 8151, NRRL B-14615, Sclerothrix phlei
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.