| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acrC_10 | acsA_1 | MPHLCCUG_03447 | MPHLCCUG_00402 | Acryloyl-CoA reductase (NADH). | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.927 |
| acrC_10 | acsA_3 | MPHLCCUG_03447 | MPHLCCUG_02499 | Acryloyl-CoA reductase (NADH). | Acetyl-coenzyme A synthetase. | 0.927 |
| acrC_10 | acsA_4 | MPHLCCUG_03447 | MPHLCCUG_04324 | Acryloyl-CoA reductase (NADH). | Acetyl-coenzyme A synthetase. | 0.925 |
| acrC_10 | acuI | MPHLCCUG_03447 | MPHLCCUG_01767 | Acryloyl-CoA reductase (NADH). | Putative acrylyl-CoA reductase AcuI. | 0.919 |
| acrC_10 | fadJ | MPHLCCUG_03447 | MPHLCCUG_00772 | Acryloyl-CoA reductase (NADH). | Fatty acid oxidation complex subunit alpha. | 0.988 |
| acrC_10 | mmsA_2 | MPHLCCUG_03447 | MPHLCCUG_04433 | Acryloyl-CoA reductase (NADH). | Methylmalonate-semialdehyde dehydrogenase (acylating). | 0.926 |
| acrC_10 | mmsB | MPHLCCUG_03447 | MPHLCCUG_01362 | Acryloyl-CoA reductase (NADH). | 3-hydroxyisobutyrate dehydrogenase. | 0.833 |
| acrC_10 | puuE_1 | MPHLCCUG_03447 | MPHLCCUG_03022 | Acryloyl-CoA reductase (NADH). | 4-aminobutyrate aminotransferase PuuE. | 0.810 |
| acsA_1 | acrC_10 | MPHLCCUG_00402 | MPHLCCUG_03447 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acryloyl-CoA reductase (NADH). | 0.927 |
| acsA_1 | acsA_3 | MPHLCCUG_00402 | MPHLCCUG_02499 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetyl-coenzyme A synthetase. | 0.916 |
| acsA_1 | acsA_4 | MPHLCCUG_00402 | MPHLCCUG_04324 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetyl-coenzyme A synthetase. | 0.909 |
| acsA_1 | acuI | MPHLCCUG_00402 | MPHLCCUG_01767 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Putative acrylyl-CoA reductase AcuI. | 0.912 |
| acsA_1 | fadJ | MPHLCCUG_00402 | MPHLCCUG_00772 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Fatty acid oxidation complex subunit alpha. | 0.908 |
| acsA_1 | mmsA_2 | MPHLCCUG_00402 | MPHLCCUG_04433 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Methylmalonate-semialdehyde dehydrogenase (acylating). | 0.943 |
| acsA_1 | mmsB | MPHLCCUG_00402 | MPHLCCUG_01362 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 3-hydroxyisobutyrate dehydrogenase. | 0.820 |
| acsA_1 | puuE_1 | MPHLCCUG_00402 | MPHLCCUG_03022 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 4-aminobutyrate aminotransferase PuuE. | 0.824 |
| acsA_3 | acrC_10 | MPHLCCUG_02499 | MPHLCCUG_03447 | Acetyl-coenzyme A synthetase. | Acryloyl-CoA reductase (NADH). | 0.927 |
| acsA_3 | acsA_1 | MPHLCCUG_02499 | MPHLCCUG_00402 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.916 |
| acsA_3 | acsA_4 | MPHLCCUG_02499 | MPHLCCUG_04324 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase. | 0.923 |
| acsA_3 | acuI | MPHLCCUG_02499 | MPHLCCUG_01767 | Acetyl-coenzyme A synthetase. | Putative acrylyl-CoA reductase AcuI. | 0.911 |