| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ackA | acsA_1 | MPHLCCUG_04643 | MPHLCCUG_00402 | Acetate kinase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.970 |
| ackA | acsA_3 | MPHLCCUG_04643 | MPHLCCUG_02499 | Acetate kinase. | Acetyl-coenzyme A synthetase. | 0.972 |
| ackA | acsA_4 | MPHLCCUG_04643 | MPHLCCUG_04324 | Acetate kinase. | Acetyl-coenzyme A synthetase. | 0.933 |
| ackA | glcB | MPHLCCUG_04643 | MPHLCCUG_02361 | Acetate kinase. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.878 |
| ackA | kgd | MPHLCCUG_04643 | MPHLCCUG_04016 | Acetate kinase. | Multifunctional 2-oxoglutarate metabolism enzyme. | 0.518 |
| ackA | korA | MPHLCCUG_04643 | MPHLCCUG_03612 | Acetate kinase. | 2-oxoglutarate oxidoreductase subunit KorA. | 0.696 |
| ackA | pta | MPHLCCUG_04643 | MPHLCCUG_04644 | Acetate kinase. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.999 |
| ackA | xpkA | MPHLCCUG_04643 | MPHLCCUG_02389 | Acetate kinase. | Xylulose-5-phosphate phosphoketolase. | 0.844 |
| acsA_1 | ackA | MPHLCCUG_00402 | MPHLCCUG_04643 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetate kinase. | 0.970 |
| acsA_1 | acsA_3 | MPHLCCUG_00402 | MPHLCCUG_02499 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetyl-coenzyme A synthetase. | 0.916 |
| acsA_1 | acsA_4 | MPHLCCUG_00402 | MPHLCCUG_04324 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acetyl-coenzyme A synthetase. | 0.909 |
| acsA_1 | bkdC | MPHLCCUG_00402 | MPHLCCUG_03660 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); Dihydrolipoyllysine-residue acyltransferase component of branched-chain alpha-ketoacid dehydrogenase complex. | 0.912 |
| acsA_1 | glcB | MPHLCCUG_00402 | MPHLCCUG_02361 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.954 |
| acsA_1 | korA | MPHLCCUG_00402 | MPHLCCUG_03612 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 2-oxoglutarate oxidoreductase subunit KorA. | 0.941 |
| acsA_1 | korB | MPHLCCUG_00402 | MPHLCCUG_03611 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 2-oxoglutarate oxidoreductase subunit KorB. | 0.914 |
| acsA_1 | pta | MPHLCCUG_00402 | MPHLCCUG_04644 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.948 |
| acsA_3 | ackA | MPHLCCUG_02499 | MPHLCCUG_04643 | Acetyl-coenzyme A synthetase. | Acetate kinase. | 0.972 |
| acsA_3 | acsA_1 | MPHLCCUG_02499 | MPHLCCUG_00402 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.916 |
| acsA_3 | acsA_4 | MPHLCCUG_02499 | MPHLCCUG_04324 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase. | 0.923 |
| acsA_3 | bkdC | MPHLCCUG_02499 | MPHLCCUG_03660 | Acetyl-coenzyme A synthetase. | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase); Dihydrolipoyllysine-residue acyltransferase component of branched-chain alpha-ketoacid dehydrogenase complex. | 0.927 |