node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OLF72315.1 | OLF77782.1 | AWH62_10800 | AWH62_03680 | Chromosomal replication initiator DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.754 |
OLF73946.1 | OLF77782.1 | AWH62_07280 | AWH62_03680 | DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.865 |
OLF73946.1 | dnaA | AWH62_07280 | AWH62_16375 | DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. | Chromosomal replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.427 |
OLF73946.1 | dnaG | AWH62_07280 | AWH62_13675 | DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. | 0.568 |
OLF73946.1 | radA | AWH62_07280 | AWH62_03670 | DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.754 |
OLF74111.1 | OLF77782.1 | AWH62_08215 | AWH62_03680 | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.726 |
OLF74111.1 | dnaX | AWH62_08215 | AWH62_01635 | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.962 |
OLF77782.1 | OLF72315.1 | AWH62_03680 | AWH62_10800 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiator DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.754 |
OLF77782.1 | OLF73946.1 | AWH62_03680 | AWH62_07280 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA helicase II; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.865 |
OLF77782.1 | OLF74111.1 | AWH62_03680 | AWH62_08215 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.726 |
OLF77782.1 | OLF77818.1 | AWH62_03680 | AWH62_03865 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DnaA family. | 0.771 |
OLF77782.1 | OLF77952.1 | AWH62_03680 | AWH62_04605 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | 0.754 |
OLF77782.1 | OLF78058.1 | AWH62_03680 | AWH62_03675 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Hypothetical protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.814 |
OLF77782.1 | dnaA | AWH62_03680 | AWH62_16375 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.974 |
OLF77782.1 | dnaG | AWH62_03680 | AWH62_13675 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. | 0.991 |
OLF77782.1 | dnaX | AWH62_03680 | AWH62_01635 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.933 |
OLF77782.1 | radA | AWH62_03680 | AWH62_03670 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.775 |
OLF77818.1 | OLF77782.1 | AWH62_03865 | AWH62_03680 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DnaA family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.771 |
OLF77818.1 | dnaA | AWH62_03865 | AWH62_16375 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DnaA family. | Chromosomal replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.669 |
OLF77952.1 | OLF77782.1 | AWH62_04605 | AWH62_03680 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.754 |