STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tap_2Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)    
Predicted Functional Partners:
glnA2
Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family.
  
  
 0.780
glnE
Bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of [...]
     
 0.745
pks5-1_3
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.645
ppsC_2
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.645
mas_2
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.645
tap_1
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
0.623
APU26076.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.580
pks7
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.575
pks8
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.575
APU28006.1
Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.575
Your Current Organism:
Mycobacterium tuberculosis variant caprae
NCBI taxonomy Id: 115862
Other names: ATCC BAA-824, CIP 105776, M. tuberculosis variant caprae, Mycobacterium bovis subsp. caprae, Mycobacterium caprae, Mycobacterium tuberculosis subsp. caprae, strain gM-1, strain spc-1
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