Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hptHypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (193 aa)    
Predicted Functional Partners:
guaA_1
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
 
 0.983
AKC37650.1
tRNA(Ile)-lysidine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.968
guaB_1
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
  
 0.957
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.953
AKC39331.1
Guanylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.950
punA
Purine nucleoside phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.935
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.930
AKC40090.1
Nucleoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.928
AKC40157.1
Adenylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.921
AKC38102.1
Nucleoside triphosphate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.920
Your Current Organism:
Mycobacteroides chelonae
NCBI taxonomy Id: 1774
Other names: ATCC 35752, CCUG 47445, CIP 104535, DSM 43804, IMET 10609, JCM 6388, M. chelonae, Mycobacterium chelonae, Mycobacterium chelonei, NCTC 946, strain CM 6388
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