Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
ksdD_13-ketosteroid-delta-1-dehydrogenase; Initiates steroid ring degradation; catalyzes the transhydrogenation of 3-keto-4-ene-steroid to 3-keto-1,4-diene-steroid e.g., progesterone to 1,4-androstadiene-3,17-dione; Derived by automated computational analysis using gene prediction method: Protein Homology. (562 aa)    
Predicted Functional Partners:
AKC40479.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.989
kshA_7
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.971
AKC37703.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.971
AKC40018.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.970
AKC37737.1
23S rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 
0.967
AKC37734.1
Lipid-transfer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.962
AKC37736.1
3-alpha,7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.949
AKC40475.1
Ketosteroid isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.940
AKC40279.1
3-ketosteroid-9-alpha-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.930
AKC38145.1
Steroid delta-isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.929
Your Current Organism:
Mycobacteroides chelonae
NCBI taxonomy Id: 1774
Other names: ATCC 35752, CCUG 47445, CIP 104535, DSM 43804, IMET 10609, JCM 6388, M. chelonae, Mycobacterium chelonae, Mycobacterium chelonei, NCTC 946, strain CM 6388
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