node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AKC40096.1 | guaA_1 | GR01_18110 | GR01_18100 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.998 |
AKC40096.1 | guaB_1 | GR01_18110 | GR01_18115 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.983 |
AKC40096.1 | guaB_2 | GR01_18110 | GR01_11545 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.961 |
AKC40096.1 | hpt | GR01_18110 | GR01_02415 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.911 |
AKC40096.1 | purA | GR01_18110 | GR01_20935 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.971 |
AKC40096.1 | purB | GR01_18110 | GR01_03255 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.614 |
AKC40096.1 | purH | GR01_18110 | GR01_04885 | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.947 |
argG | asnB_2 | GR01_11215 | GR01_09675 | Argininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.924 |
argG | purA | GR01_11215 | GR01_20935 | Argininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.932 |
argG | pyrB | GR01_11215 | GR01_13305 | Argininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.911 |
asnB_2 | argG | GR01_09675 | GR01_11215 | Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Argininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.924 |
asnB_2 | guaA_1 | GR01_09675 | GR01_18100 | Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.598 |
asnB_2 | purA | GR01_09675 | GR01_20935 | Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.925 |
asnB_2 | pyrB | GR01_09675 | GR01_13305 | Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.924 |
guaA_1 | AKC40096.1 | GR01_18100 | GR01_18110 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
guaA_1 | asnB_2 | GR01_18100 | GR01_09675 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.598 |
guaA_1 | guaB_1 | GR01_18100 | GR01_18115 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA_1 | guaB_2 | GR01_18100 | GR01_11545 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.998 |
guaA_1 | hpt | GR01_18100 | GR01_02415 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Hypoxanthine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.973 |
guaA_1 | purA | GR01_18100 | GR01_20935 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.947 |